C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transducin-like enhancer of split 6, homolog of Drosophila E(spl)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034758 Tle6 10090 - 10:81590904-81601073 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000072020 Tle6-001 81590905-81600900 protein_coding
  ENSMUST00000124724 Tle6-013 81594239-81595808 retained_intron
  ENSMUST00000127546 Tle6-006 81595996-81601073 protein_coding
  ENSMUST00000128278 Tle6-003 81590904-81597590 processed_transcript
  ENSMUST00000129282 Tle6-009 81590905-81592715 processed_transcript
  ENSMUST00000131530 Tle6-011 81595209-81597338 processed_transcript
  ENSMUST00000134457 Tle6-014 81593919-81595244 retained_intron
  ENSMUST00000135008 Tle6-008 81595953-81597367 processed_transcript
  ENSMUST00000137631 Tle6-004 81590907-81597345 processed_transcript
  ENSMUST00000142948 Tle6-002 81590904-81600875 protein_coding
  ENSMUST00000146239 Tle6-015 81591133-81592818 retained_intron
  ENSMUST00000149721 Tle6-012 81595229-81597331 processed_transcript
  ENSMUST00000151858 Tle6-007 81595993-81600857 protein_coding
  ENSMUST00000153379 Tle6-005 81590905-81595415 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000072020ENSMUST00000124724ENSMUST00000127546ENSMUST00000128278ENSMUST00000129282ENSMUST00000131530ENSMUST00000134457ENSMUST00000135008ENSMUST00000137631ENSMUST00000142948ENSMUST00000146239ENSMUST00000149721ENSMUST00000153379
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000072020 0.959±0.00 N/A 1.557±0.10 0.196±0.00 0.800±0.15 1.189±0.00 0.832±0.30 0.132±0.00 0.569±0.13 1.922±0.29 1.198±0.51 8.992±2.55 1.260±0.52 0.842±0.13
ENSMUST00000124724 1.514±0.00 9.935±4.14 N/A 0.352±0.00 N/A 3.506±0.00 N/A N/A 0.617±0.00 4.150±0.72 N/A N/A N/A N/A
ENSMUST00000127546 N/A N/A N/A N/A N/A N/A 2.379±0.00 N/A N/A N/A 1.114±0.00 N/A N/A 2.340±0.00
ENSMUST00000128278 N/A 2.445±0.13 N/A 0.132±0.00 N/A 0.981±0.00 N/A N/A N/A N/A N/A N/A 1.010±0.00 N/A
ENSMUST00000129282 1.882±0.00 N/A N/A 0.801±0.00 3.625±0.00 N/A 3.384±0.55 0.949±0.12 1.450±0.00 N/A 1.644±0.00 41.601±8.64 5.861±0.30 1.809±0.00
ENSMUST00000131530 N/A N/A N/A 0.756±0.00 N/A N/A N/A N/A N/A N/A N/A 42.902±0.00 7.241±2.59 2.046±0.00
ENSMUST00000134457 1.904±0.50 11.223±4.93 N/A 0.887±0.43 3.501±0.77 4.412±0.00 1.873±0.24 N/A N/A 5.099±0.93 N/A 27.376±8.62 6.163±2.07 N/A
ENSMUST00000135008 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.587±0.00 N/A
ENSMUST00000137631 0.533±0.00 N/A 1.337±0.04 0.258±0.14 0.634±0.00 N/A 0.367±0.00 0.255±0.09 N/A N/A N/A N/A N/A N/A
ENSMUST00000142948 N/A N/A N/A N/A N/A N/A N/A 0.305±0.00 0.460±0.20 N/A 0.565±0.00 7.064±1.54 N/A N/A
ENSMUST00000146239 1.932±0.00 12.628±4.43 N/A N/A 4.528±0.20 5.766±0.59 N/A N/A 0.944±0.00 6.668±0.48 N/A N/A N/A N/A
ENSMUST00000149721 N/A N/A 5.599±0.00 N/A N/A N/A N/A 1.235±0.00 N/A N/A 1.436±0.32 32.668±7.00 2.070±0.00 N/A
ENSMUST00000153379 1.059±0.26 8.067±3.96 4.646±0.77 0.524±0.35 1.615±0.82 3.877±0.50 1.408±0.27 0.337±0.00 1.044±0.30 3.973±1.67 1.037±0.56 24.741±3.55 2.080±0.44 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005938 IDA cell cortex
GO:0043234 IDA protein complex
GO:0045666 IGI positive regulation of neuron differentiation
GO:0050769 IMP positive regulation of neurogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019588 chico chico protein_coding Danio_rerio
ENSDARG00000021805 aes amino-terminal enhancer of split protein_coding Danio_rerio
ENSG00000104953 TLE6 transducin-like enhancer of split 6 protein_coding Homo_sapiens

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