C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chemokine (C-X-C motif) ligand 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034855 Cxcl10 10090 - 5:92346638-92348889 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000038816 Cxcl10-001 92346638-92348882 protein_coding
  ENSMUST00000118006 Cxcl10-002 92347474-92348889 protein_coding
  ENSMUST00000138169 Cxcl10-003 92348001-92348882 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonKidneyLiverLungOvaryPlacentaENSMUST00000038816ENSMUST00000118006ENSMUST00000138169
Transcript ID Adipose Adrenal Brain Breast Colon Kidney Liver Lung Ovary Placenta
ENSMUST00000038816 8.662±0.94 1.100±0.25 0.232±0.08 6.575±0.80 1.361±0.44 6.725±2.12 7.260±3.72 2.124±0.00 2.410±1.02 0.558±0.28
ENSMUST00000118006 N/A 1.385±0.00 N/A N/A N/A N/A N/A N/A 2.651±0.00 N/A
ENSMUST00000138169 N/A 2.740±0.00 N/A N/A N/A N/A 4.984±2.02 N/A 4.858±0.77 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00071M CIL_00071M_0002 CGP 5:92321331-92414628
CIL_0008VL CIL_0008VL_0002 VISTA 5:92327753-92928377
CIL_00071H CIL_00071H_0002 CGP 5:92331827-92414628

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002690 IEA positive regulation of leukocyte chemotaxis
GO:0005515 IEA protein binding
GO:0005615 IDA extracellular space
GO:0006935 ISS chemotaxis
GO:0006954 IEA inflammatory response
GO:0007165 IEA signal transduction
GO:0007186 ISS G-protein coupled receptor signaling pathway
GO:0008009 ISS chemokine activity
GO:0008201 IEA heparin binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0009306 IEA protein secretion
GO:0009409 IEA response to cold
GO:0009615 IEA response to virus
GO:0009897 IDA external side of plasma membrane
GO:0010332 IEA response to gamma radiation
GO:0010818 IEA T cell chemotaxis
GO:0010996 IEA response to auditory stimulus
GO:0016525 IEA negative regulation of angiogenesis
GO:0030335 IEA positive regulation of cell migration
GO:0030816 ISS positive regulation of cAMP metabolic process
GO:0032496 IEA response to lipopolysaccharide
GO:0033280 IEA response to vitamin D
GO:0034605 IEA cellular response to heat
GO:0042127 ISS regulation of cell proliferation
GO:0043950 ISS positive regulation of cAMP-mediated signaling
GO:0045662 IMP negative regulation of myoblast differentiation
GO:0048248 ISS CXCR3 chemokine receptor binding
GO:0051281 ISS positive regulation of release of sequestered calcium ion into cytosol
GO:0051607 IDA defense response to virus
GO:0070098 IEA chemokine-mediated signaling pathway
GO:0071222 ISO cellular response to lipopolysaccharide
GO:1901740 IMP negative regulation of myoblast fusion
GO:2000406 ISO positive regulation of T cell migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000169245 CXCL10 chemokine (C-X-C motif) ligand 10 protein_coding Homo_sapiens

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