C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 24-dehydrocholesterol reductase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034926 Dhcr24 10090 + 4:106561038-106589113 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000047973 Dhcr24-001 106561038-106589113 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000047973
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000047973 20.069±4.13 153.897±50.67 24.377±2.55 27.004±2.45 14.253±2.50 67.771±10.46 1.749±0.23 91.404±9.70 179.583±125.99 37.450±1.45 0.955±0.07 53.671±16.16 62.649±15.52 8.408±3.03

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000246 IEA delta24(24-1) sterol reductase activity
GO:0005634 ISS nucleus
GO:0005737 IEA cytoplasm
GO:0005783 ISS endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005829 IEA cytosol
GO:0005856 IEA cytoskeleton
GO:0006695 IEA cholesterol biosynthetic process
GO:0006979 ISS response to oxidative stress
GO:0007265 IEA Ras protein signal transduction
GO:0008104 IMP protein localization
GO:0008202 IEA steroid metabolic process
GO:0008203 IMP cholesterol metabolic process
GO:0008285 IEA negative regulation of cell proliferation
GO:0008762 IEA UDP-N-acetylmuramate dehydrogenase activity
GO:0009725 IEA response to hormone
GO:0009888 ISS tissue development
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016125 IMP sterol metabolic process
GO:0016628 ISO oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
GO:0019899 ISS enzyme binding
GO:0030539 IMP male genitalia development
GO:0031639 IMP plasminogen activation
GO:0042605 ISS peptide antigen binding
GO:0042987 IMP amyloid precursor protein catabolic process
GO:0043066 ISS negative regulation of apoptotic process
GO:0043154 ISS negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043588 IMP skin development
GO:0050614 IEA delta24-sterol reductase activity
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0055114 IEA oxidation-reduction process
GO:0061024 IMP membrane organization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013236 dhcr24 24-dehydrocholesterol reductase protein_coding Danio_rerio
ENSG00000116133 DHCR24 24-dehydrocholesterol reductase protein_coding Homo_sapiens

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