C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CCAAT/enhancer binding protein (C/EBP), alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034957 Cebpa 10090 + 7:35119293-35121926 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000042985 Cebpa-201 35119293-35121926 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000042985
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000042985 173.827±70.59 164.458±60.40 17.562±2.00 1.552±0.54 212.461±108.93 30.985±3.08 5.218±2.39 22.047±4.16 78.894±50.62 82.051±22.06 2.508±1.20 72.534±22.50 11.904±8.44 1.069±0.50

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000050 IDA urea cycle
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001889 IMP liver development
GO:0001892 IGI embryonic placenta development
GO:0003677 IDA DNA binding
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IDA transcription factor complex
GO:0006351 NAS transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006953 IEA acute-phase response
GO:0007005 IMP mitochondrion organization
GO:0007584 IEA response to nutrient
GO:0008134 ISS transcription factor binding
GO:0008203 IMP cholesterol metabolic process
GO:0008285 IMP negative regulation of cell proliferation
GO:0016363 IEA nuclear matrix
GO:0019221 NAS cytokine-mediated signaling pathway
GO:0019904 IEA protein domain specific binding
GO:0030099 IDA myeloid cell differentiation
GO:0030154 IEA cell differentiation
GO:0030225 IMP macrophage differentiation
GO:0030324 IMP lung development
GO:0031100 IEA organ regeneration
GO:0032403 IEA protein complex binding
GO:0033274 IEA response to vitamin B2
GO:0035189 IEA Rb-E2F complex
GO:0042127 IMP regulation of cell proliferation
GO:0042803 IDA protein homodimerization activity
GO:0043234 IEA protein complex
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045444 IDA fat cell differentiation
GO:0045600 IDA positive regulation of fat cell differentiation
GO:0045669 IDA positive regulation of osteoblast differentiation
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0045945 IEA positive regulation of transcription from RNA polymerase III promoter
GO:0046982 IEA protein heterodimerization activity
GO:0048469 IMP cell maturation
GO:0048839 IDA inner ear development
GO:0050872 IMP white fat cell differentiation
GO:0050873 IDA brown fat cell differentiation
GO:0051384 IEA response to glucocorticoid
GO:0071285 IDA cellular response to lithium ion
GO:0071407 IDA cellular response to organic cyclic compound
GO:0071837 IEA HMG box domain binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036074 cebpa CCAAT/enhancer binding protein (C/EBP), alpha protein_coding Danio_rerio
ENSG00000245848 CEBPA CCAAT/enhancer binding protein (C/EBP), alpha protein_coding Homo_sapiens

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