C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hexokinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037012 Hk1 10090 - 10:62268855-62379908 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000072357 Hk1-201 62269108-62358362 protein_coding
  ENSMUST00000099691 Hk1-014 62268855-62340542 protein_coding
  ENSMUST00000116238 Hk1-001 62269104-62379908 protein_coding
  ENSMUST00000130091 Hk1-007 62315476-62375100 protein_coding
  ENSMUST00000130422 Hk1-013 62269909-62342722 protein_coding
  ENSMUST00000132926 Hk1-004 62315476-62379852 protein_coding
  ENSMUST00000133429 Hk1-003 62315476-62379852 protein_coding
  ENSMUST00000134447 Hk1-008 62315476-62375100 protein_coding
  ENSMUST00000134877 Hk1-005 62315476-62375100 protein_coding
  ENSMUST00000135317 Hk1-006 62315476-62375100 protein_coding
  ENSMUST00000136548 Hk1-009 62315476-62375100 protein_coding
  ENSMUST00000139228 Hk1-017 62296093-62327767 protein_coding
  ENSMUST00000140383 Hk1-011 62315476-62375100 protein_coding
  ENSMUST00000142527 Hk1-016 62296958-62342708 retained_intron
  ENSMUST00000143179 Hk1-015 62296713-62342699 protein_coding
  ENSMUST00000143236 Hk1-002 62315476-62379852 protein_coding
  ENSMUST00000149534 Hk1-012 62315521-62362274 protein_coding
  ENSMUST00000152761 Hk1-018 62295860-62318393 protein_coding
  ENSMUST00000154489 Hk1-010 62315476-62375100 protein_coding
  ENSMUST00000161160 Hk1-019 62284609-62290329 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000072357ENSMUST00000099691ENSMUST00000116238ENSMUST00000130422ENSMUST00000161160
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000072357 6.910±1.30 10.958±1.44 11.242±0.00 17.314±12.02 11.696±5.78 39.777±4.77 13.649±9.02 19.649±6.08 8.989±10.30 15.021±1.96 0.805±0.42 12.939±4.80 18.107±12.79 110.837±14.78
ENSMUST00000099691 4.574±1.71 1.664±0.33 9.578±0.57 27.485±27.69 4.024±0.53 10.928±2.80 9.806±1.56 7.693±1.10 2.899±3.06 5.316±0.54 0.746±0.31 4.224±1.77 12.252±7.28 N/A
ENSMUST00000116238 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 203.615±70.07
ENSMUST00000130422 N/A N/A N/A 70.906±0.00 N/A N/A N/A N/A 10.924±5.66 N/A 0.379±0.07 13.912±2.04 8.331±6.04 240.292±161.37
ENSMUST00000161160 N/A N/A N/A N/A N/A N/A N/A N/A 0.416±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007TI CIL_0007TI_0002 VISTA 10:61828052-62430842
CIL_000742 CIL_000742_0002 CGP 10:62252438-62379908
CIL_0006RG CIL_0006RG_0002 CGP 10:62268855-62422491

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001678 IBA cellular glucose homeostasis
GO:0004340 IBA glucokinase activity
GO:0004396 TAS hexokinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005739 IDA mitochondrion
GO:0005741 IEA mitochondrial outer membrane
GO:0005829 IDA cytosol
GO:0005929 IDA cilium
GO:0006096 TAS glycolytic process
GO:0008865 IBA fructokinase activity
GO:0019158 IBA mannokinase activity
GO:0045121 IDA membrane raft
GO:0046835 IBA:IEA carbohydrate phosphorylation
GO:0051156 IBA glucose 6-phosphate metabolic process
GO:0061621 IC canonical glycolysis
GO:0097228 IDA sperm principal piece

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039452 hk1 hexokinase 1 protein_coding Danio_rerio
ENSG00000156515 HK1 hexokinase 1 protein_coding Homo_sapiens

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