C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sprouty homolog 1 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037211 Spry1 10090 + 3:37639947-37644598 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000038569 Spry1-001 37639958-37644598 protein_coding
  ENSMUST00000108107 Spry1-003 37640080-37644598 protein_coding
  ENSMUST00000108109 Spry1-002 37639947-37644598 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000038569ENSMUST00000108107ENSMUST00000108109
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000038569 12.584±4.50 10.545±2.45 11.604±0.17 2.985±0.91 7.262±1.46 6.877±0.70 5.184±2.65 9.687±2.63 1.603±1.19 24.250±4.73 4.984±2.37 7.593±3.24 2.681±1.33 N/A
ENSMUST00000108107 3.266±0.65 2.633±0.41 2.934±0.01 1.273±0.04 3.842±0.95 2.496±0.31 1.575±0.00 N/A 0.654±0.38 5.963±0.52 1.348±0.20 3.418±0.83 0.888±0.00 0.312±0.12
ENSMUST00000108109 5.493±2.88 4.302±1.15 4.310±0.24 1.163±0.53 7.264±5.15 3.765±0.62 4.211±0.92 8.595±2.82 1.248±0.95 17.905±5.70 6.401±1.75 6.300±2.14 1.684±0.83 1.088±0.57

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007V2 CIL_0007V2_0002 VISTA 3:37371698-37974083
CIL_0007AG CIL_0007AG_0002 CGP 3:37419896-37644598
CIL_00099R CIL_00099R_0002 VISTA 3:37594700-38198826

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000132 IGI establishment of mitotic spindle orientation
GO:0001656 IGI metanephros development
GO:0001657 IGI ureteric bud development
GO:0001759 IMP organ induction
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0008285 IDA negative regulation of cell proliferation
GO:0016020 IEA membrane
GO:0034261 IDA negative regulation of Ras GTPase activity
GO:0040037 IDA negative regulation of fibroblast growth factor receptor signaling pathway
GO:0043407 IDA negative regulation of MAP kinase activity
GO:0046580 IDA negative regulation of Ras protein signal transduction
GO:0051387 IDA negative regulation of neurotrophin TRK receptor signaling pathway
GO:0060449 IGI bud elongation involved in lung branching
GO:0070373 IDA negative regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000024286 spry1 sprouty homolog 1 (Drosophila) protein_coding Danio_rerio
ENSG00000164056 SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) protein_coding Homo_sapiens

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