C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chloride intracellular channel 4 (mitochondrial)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037242 Clic4 10090 - 4:135213969-135272814 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000037099 Clic4-001 135213969-135272814 protein_coding
  ENSMUST00000143370 Clic4-002 135223464-135272814 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000037099
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000037099 67.214±8.92 39.768±2.58 70.391±3.48 16.631±5.85 48.441±3.68 39.096±1.31 59.755±18.09 50.016±2.20 26.696±9.83 139.749±24.47 7.704±0.77 47.018±13.01 83.027±40.09 10.331±3.25

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ZX CIL_0007ZX_0002 VISTA 4:134905845-135507207

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IMP angiogenesis
GO:0001886 IMP endothelial cell morphogenesis
GO:0005247 IEA voltage-gated chloride channel activity
GO:0005254 ISO chloride channel activity
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005737 ISS cytoplasm
GO:0005739 IDA mitochondrion
GO:0005813 IEA centrosome
GO:0005829 IEA cytosol
GO:0005886 IEA plasma membrane
GO:0005902 IEA microvillus
GO:0005911 IEA cell-cell junction
GO:0006821 ISO chloride transport
GO:0007035 IMP vacuolar acidification
GO:0009566 IMP fertilization
GO:0009986 IEA cell surface
GO:0015630 IEA microtubule cytoskeleton
GO:0016363 IEA nuclear matrix
GO:0030216 IMP keratinocyte differentiation
GO:0030336 ISS negative regulation of cell migration
GO:0030496 IEA midbody
GO:0031410 IEA cytoplasmic vesicle
GO:0034707 IEA chloride channel complex
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035264 IMP multicellular organism growth
GO:0044070 IEA regulation of anion transport
GO:0045177 IEA apical part of cell
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048754 IMP branching morphogenesis of an epithelial tube
GO:0061299 IMP retina vasculature morphogenesis in camera-type eye
GO:0070062 IEA extracellular vesicular exosome
GO:0071277 IEA cellular response to calcium ion
GO:1902476 IEA chloride transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022995 clic4 chloride intracellular channel 4 protein_coding Danio_rerio
ENSG00000169504 CLIC4 chloride intracellular channel 4 protein_coding Homo_sapiens

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