C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: heart and neural crest derivatives expressed transcript 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037335 Hand1 10090 - 11:57828705-57832818 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000036917 Hand1-001 57828707-57832147 protein_coding
  ENSMUST00000108845 Hand1-002 57831694-57832818 protein_coding
  ENSMUST00000160392 Hand1-201 57828705-57832818 protein_coding

Mus musculus EnsemblGRCm38

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Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainColonHeartKidneyLiverLungPlacentaTestisENSMUST00000036917ENSMUST00000108845ENSMUST00000160392
Transcript ID Adrenal Bladder Brain Colon Heart Kidney Liver Lung Placenta Testis
ENSMUST00000036917 8.659±3.54 0.269±0.04 0.010±0.00 4.673±0.62 N/A 0.193±0.05 0.245±0.16 N/A 116.263±49.00 0.170±0.14
ENSMUST00000108845 N/A N/A 0.048±0.00 N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000160392 N/A 0.168±0.06 0.013±0.00 N/A 0.015±0.00 0.092±0.05 0.051±0.00 0.023±0.01 139.990±48.86 0.216±0.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009C8 CIL_0009C8_0002 VISTA 11:57350678-57952744
CIL_00094E CIL_00094E_0002 VISTA 11:57350713-57952688
CIL_00099I CIL_00099I_0002 VISTA 11:57547462-58147793
CIL_00088D CIL_00088D_0002 VISTA 11:57627590-58231336
CIL_0001UK CIL_0001UK_0002 CGP 11:57801637-57832818
CIL_00023W CIL_00023W_0002 CGP 11:57828705-58062034

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0001525 IMP angiogenesis
GO:0001701 IMP in utero embryonic development
GO:0001707 IMP mesoderm formation
GO:0001709 NAS cell fate determination
GO:0001824 IEA blastocyst development
GO:0001829 IEA trophectodermal cell differentiation
GO:0001947 IMP heart looping
GO:0003007 TAS heart morphogenesis
GO:0003144 IMP embryonic heart tube formation
GO:0003218 IEA cardiac left ventricle formation
GO:0003219 IEA cardiac right ventricle formation
GO:0003677 IDA DNA binding
GO:0003713 IDA transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005730 IDA nucleolus
GO:0005737 IEA cytoplasm
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0007507 IGI heart development
GO:0008134 IPI transcription factor binding
GO:0019899 IPI enzyme binding
GO:0030154 IGI cell differentiation
GO:0035050 IMP embryonic heart tube development
GO:0042475 IGI odontogenesis of dentin-containing tooth
GO:0042802 IPI identical protein binding
GO:0042803 IDA:IPI protein homodimerization activity
GO:0043425 IPI bHLH transcription factor binding
GO:0043433 IDA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0043565 IGI sequence-specific DNA binding
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis
GO:0060411 IEA cardiac septum morphogenesis
GO:0060485 IGI mesenchyme development
GO:0060536 IGI cartilage morphogenesis
GO:0060707 IDA:IMP trophoblast giant cell differentiation
GO:0061371 IMP determination of heart left/right asymmetry

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000113196 HAND1 heart and neural crest derivatives expressed 1 protein_coding Homo_sapiens

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