C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysine (K)-specific demethylase 6A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037369 Kdm6a 10090 + X:18162575-18279936 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000044484 Kdm6a-001 18162575-18279936 protein_coding
  ENSMUST00000052368 Kdm6a-002 18162575-18279936 protein_coding
  ENSMUST00000130978 Kdm6a-003 18162648-18258968 retained_intron
  ENSMUST00000155161 Kdm6a-004 18274512-18278260 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000044484ENSMUST00000052368ENSMUST00000130978
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000044484 3.260±1.92 4.289±1.12 3.450±0.69 3.535±2.05 3.785±1.85 2.236±1.30 1.764±0.35 2.869±0.38 3.515±2.17 2.265±0.14 1.318±0.27 4.261±1.85 3.290±1.28 0.434±0.18
ENSMUST00000052368 N/A 2.162±1.40 N/A N/A 1.207±0.07 N/A N/A 0.633±0.00 0.516±0.03 N/A 0.368±0.00 2.474±0.52 1.049±0.21 0.448±0.00
ENSMUST00000130978 2.404±1.08 1.201±0.23 N/A 1.165±0.01 3.567±2.40 1.189±0.16 0.910±0.14 1.314±0.42 0.389±0.02 1.239±0.28 N/A 3.226±1.02 0.710±0.00 0.232±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005QA CIL_0005QA_0002 CGP X:18145857-18279936
CIL_0003JA CIL_0003JA_0003 CGP X:18162575-18461397

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001701 IMP in utero embryonic development
GO:0001843 IMP neural tube closure
GO:0003007 IMP heart morphogenesis
GO:0003016 IMP respiratory system process
GO:0005515 IPI protein binding
GO:0005634 ISO nucleus
GO:0007507 IMP heart development
GO:0010468 IMP regulation of gene expression
GO:0021915 IMP neural tube development
GO:0032525 IMP somite rostral/caudal axis specification
GO:0035097 ISO histone methyltransferase complex
GO:0035264 IMP multicellular organism growth
GO:0042802 IDA identical protein binding
GO:0046872 IEA metal ion binding
GO:0048333 IMP mesodermal cell differentiation
GO:0048568 IMP embryonic organ development
GO:0048570 IMP notochord morphogenesis
GO:0051213 IEA dioxygenase activity
GO:0055114 IEA oxidation-reduction process
GO:0060070 IMP canonical Wnt signaling pathway
GO:0071557 IEA histone H3-K27 demethylation
GO:0071558 IDA histone demethylase activity (H3-K27 specific)
GO:0072358 IMP cardiovascular system development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059794 kdm6al lysine (K)-specific demethylase 6A, like protein_coding Danio_rerio
ENSDARG00000061759 kdm6a lysine (K)-specific demethylase 6A protein_coding Danio_rerio
ENSG00000147050 KDM6A lysine (K)-specific demethylase 6A protein_coding Homo_sapiens

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