| Transcript ID | Brain |
|---|---|
| ENSMUST00000047664 | 54.071±0.00 |
C-It-Loci: A knowledge database for tissue-enriched loci.
Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main
Gene Info | |||||
|---|---|---|---|---|---|
| Description: | Rho guanine nucleotide exchange factor (GEF) 4 | ||||
| Gene Accession | Gene Name | Tax ID | Strand | Position | Gene Biotype |
ENSMUSG00000037509  |
Arhgef4 | 10090 | + |
1:34678188-34813309  |
protein_coding |
| Transcript Accession | Transcript Name | Position | Transcript Biotype | ||
| ENSMUST00000047664 |
Arhgef4-001 | 34801704-34813309 | protein_coding | ||
| ENSMUST00000159021 |
Arhgef4-006 | 34750881-34807144 | protein_coding | ||
| ENSMUST00000159059 |
Arhgef4-007 | 34801722-34806698 | retained_intron | ||
| ENSMUST00000159747 |
Arhgef4-004 | 34678188-34812739 | protein_coding | ||
| ENSMUST00000160855 |
Arhgef4-003 | 34801741-34808911 | nonsense_mediated_decay | ||
| ENSMUST00000162599 |
Arhgef4-005 | 34732115-34811829 | protein_coding | ||
| ENSMUST00000162760 |
Arhgef4-002 | 34801721-34809218 | retained_intron | ||
Expression Patterns
|
Conserved Regions | |||
|---|---|---|---|
| Region ID | Sub-Region | Region Type | Position |
| CIL_0001J9 | CIL_0001J9_0002 | CGP | 1:34579727-34813309 |
| CIL_0001J8 | CIL_0001J8_0002 | CGP | 1:34678188-34843065 |
Gene Ontology |
||
|---|---|---|
| GO ID | Evidence Type | GO Description |
| GO:0005085 | ISS | guanyl-nucleotide exchange factor activity |
| GO:0005089 | IEA | Rho guanyl-nucleotide exchange factor activity |
| GO:0005737 | IEA | cytoplasm |
| GO:0019904 | IEA | protein domain specific binding |
| GO:0030032 | ISS | lamellipodium assembly |
| GO:0030676 | ISS | Rac guanyl-nucleotide exchange factor activity |
| GO:0032321 | IEA | positive regulation of Rho GTPase activity |
| GO:0032855 | ISS | positive regulation of Rac GTPase activity |
| GO:0035556 | IEA | intracellular signal transduction |
| GO:0043547 | ISS | positive regulation of GTPase activity |
| GO:0046847 | ISS | filopodium assembly |
Homologs | |||||
| ENSEMBL Accession | Gene Name | Description | Biotype | Species | |
|
ENSDARG00000012914
|
arhgef4 | Rho guanine nucleotide exchange factor (GEF) 4 | protein_coding | Danio_rerio | |
|
ENSG00000136002
|
ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 | protein_coding | Homo_sapiens | |
