C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: catenin (cadherin associated protein), alpha 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037815 Ctnna1 10090 + 18:35118888-35254773 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000042345 Ctnna1-201 35118888-35254773 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000042345
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000042345 32.302±7.59 30.063±2.58 69.578±10.17 15.053±3.43 22.654±6.22 65.858±3.32 72.752±4.98 39.662±2.57 16.774±2.20 92.410±1.25 10.276±0.75 51.882±33.79 126.767±67.79 4.899±3.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005DA CIL_0005DA_0002 CGP 18:34937414-35254773
CIL_00062R CIL_00062R_0003 CGP 18:35118888-35254773

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001541 IEA ovarian follicle development
GO:0001669 IEA acrosomal vesicle
GO:0005198 IEA structural molecule activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005911 IEA cell-cell junction
GO:0005912 IDA adherens junction
GO:0005913 IDA cell-cell adherens junction
GO:0005915 IDA zonula adherens
GO:0005925 IEA focal adhesion
GO:0007163 IMP establishment or maintenance of cell polarity
GO:0007406 IGI negative regulation of neuroblast proliferation
GO:0007568 IEA aging
GO:0008013 IEA beta-catenin binding
GO:0008584 IEA male gonad development
GO:0014070 IEA response to organic cyclic compound
GO:0014704 IDA intercalated disc
GO:0015629 IEA actin cytoskeleton
GO:0016264 IEA gap junction assembly
GO:0016342 IEA catenin complex
GO:0017166 IEA vinculin binding
GO:0030027 IDA lamellipodium
GO:0031103 IEA axon regeneration
GO:0034613 IMP cellular protein localization
GO:0042127 IGI regulation of cell proliferation
GO:0042475 IEA odontogenesis of dentin-containing tooth
GO:0043066 IMP negative regulation of apoptotic process
GO:0043297 IMP apical junction assembly
GO:0043627 IEA response to estrogen
GO:0044822 IEA poly(A) RNA binding
GO:0045295 IEA gamma-catenin binding
GO:0045296 IEA cadherin binding
GO:0045880 IGI positive regulation of smoothened signaling pathway
GO:0051015 IDA actin filament binding
GO:0051291 IEA protein heterooligomerization
GO:0071681 IEA cellular response to indole-3-methanol
GO:0090136 IMP epithelial cell-cell adhesion
GO:2000146 IMP negative regulation of cell motility
GO:2001045 IMP negative regulation of integrin-mediated signaling pathway
GO:2001240 IMP negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
GO:2001241 IMP positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077846 ctnna1 catenin (cadherin-associated protein), alpha 1 protein_coding Danio_rerio
ENSG00000044115 CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa protein_coding Homo_sapiens

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