C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: absent in melanoma 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037860 Aim2 10090 + 1:173350879-173466040 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000135370 Aim2-003 173455488-173456165 processed_transcript
  ENSMUST00000147604 Aim2-001 173350879-173466040 protein_coding
  ENSMUST00000151176 Aim2-002 173454971-173455595 protein_coding
  ENSMUST00000166137 Aim2-201 173455354-173466032 protein_coding
  ENSMUST00000173023 Aim2-005 173420598-173459719 protein_coding
  ENSMUST00000174263 Aim2-004 173419196-173427781 processed_transcript

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000135370ENSMUST00000147604ENSMUST00000151176ENSMUST00000166137ENSMUST00000173023
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000135370 N/A 0.303±0.00 N/A N/A N/A N/A N/A 0.301±0.10 N/A N/A N/A 0.582±0.00 N/A 0.146±0.00
ENSMUST00000147604 N/A N/A N/A 0.193±0.00 0.794±0.00 N/A 0.120±0.00 N/A 0.301±0.04 N/A N/A N/A 0.073±0.00 N/A
ENSMUST00000151176 N/A N/A N/A N/A N/A N/A N/A 0.552±0.22 0.397±0.00 N/A N/A 0.841±0.07 N/A N/A
ENSMUST00000166137 0.674±0.00 0.173±0.08 0.403±0.09 0.787±0.19 1.703±1.12 4.653±2.21 0.498±0.00 0.173±0.12 1.157±0.90 0.704±0.30 0.173±0.09 0.451±0.22 0.309±0.12 0.111±0.07
ENSMUST00000173023 N/A 0.217±0.00 N/A 0.548±0.05 N/A 4.461±0.52 0.255±0.00 0.245±0.15 1.377±0.83 N/A 0.080±0.00 0.745±0.00 0.377±0.15 0.094±0.04

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002218 IDA activation of innate immune response
GO:0002230 IMP positive regulation of defense response to virus by host
GO:0003690 IDA double-stranded DNA binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006915 IEA apoptotic process
GO:0006954 IEA inflammatory response
GO:0032088 IEA negative regulation of NF-kappaB transcription factor activity
GO:0032461 IEA positive regulation of protein oligomerization
GO:0032731 IMP positive regulation of interleukin-1 beta production
GO:0033209 IEA tumor necrosis factor-mediated signaling pathway
GO:0035458 IDA cellular response to interferon-beta
GO:0035690 ISO cellular response to drug
GO:0042802 IPI identical protein binding
GO:0045087 IEA innate immune response
GO:0050702 ISO interleukin-1 beta secretion
GO:0050718 IGI positive regulation of interleukin-1 beta secretion
GO:0051092 IEA positive regulation of NF-kappaB transcription factor activity
GO:0070269 IDA pyroptosis
GO:0097169 IDA AIM2 inflammasome complex
GO:2001056 IMP positive regulation of cysteine-type endopeptidase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000163568 AIM2 absent in melanoma 2 protein_coding Homo_sapiens

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