C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysophosphatidic acid receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038668 Lpar1 10090 - 4:58435255-58553898 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000055018 Lpar1-001 58435255-58553357 protein_coding
  ENSMUST00000107570 Lpar1-005 58435255-58499403 protein_coding
  ENSMUST00000107571 Lpar1-002 58435255-58553311 protein_coding
  ENSMUST00000107574 Lpar1-004 58435255-58553628 protein_coding
  ENSMUST00000107575 Lpar1-003 58435255-58553553 protein_coding
  ENSMUST00000145361 Lpar1-007 58487134-58553184 protein_coding
  ENSMUST00000147354 Lpar1-006 58487100-58553898 protein_coding
  ENSMUST00000155170 Lpar1-008 58487045-58548401 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000055018ENSMUST00000107570ENSMUST00000107574ENSMUST00000107575ENSMUST00000145361
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000055018 16.699±9.57 8.577±2.80 18.390±4.37 3.019±0.80 15.762±4.27 28.520±3.61 3.841±1.44 4.139±0.31 0.529±0.27 10.578±1.15 0.732±0.31 8.670±4.98 2.802±2.20 4.449±0.82
ENSMUST00000107570 N/A N/A N/A 3.727±0.00 7.358±0.00 N/A N/A N/A 0.143±0.03 N/A 0.590±0.50 1.743±0.42 3.143±0.70 4.196±1.54
ENSMUST00000107574 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.457±0.00 N/A N/A
ENSMUST00000107575 N/A N/A 2.150±0.00 N/A N/A N/A N/A 0.779±0.00 0.136±0.04 N/A 0.844±0.10 2.188±0.35 N/A N/A
ENSMUST00000145361 N/A 14.620±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00016H CIL_00016H_0002 CGP 4:58285960-58553898
CIL_00093E CIL_00093E_0002 VISTA 4:58366631-58972430
CIL_00016L CIL_00016L_0002 CGP 4:58435255-58785720

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 IDA activation of MAPK activity
GO:0001965 IEA G-protein alpha-subunit binding
GO:0005515 IPI protein binding
GO:0005543 IEA phospholipid binding
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0007186 IDA G-protein coupled receptor signaling pathway
GO:0009986 ISS cell surface
GO:0010942 IEA positive regulation of cell death
GO:0010977 IEA negative regulation of neuron projection development
GO:0016021 IEA integral component of membrane
GO:0022008 IEA neurogenesis
GO:0030139 IEA endocytic vesicle
GO:0030165 IPI PDZ domain binding
GO:0032060 IGI bleb assembly
GO:0035025 IDA positive regulation of Rho protein signal transduction
GO:0042552 IEA myelination
GO:0043065 IEA positive regulation of apoptotic process
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043197 IEA dendritic spine
GO:0043198 IEA dendritic shaft
GO:0043410 IDA positive regulation of MAPK cascade
GO:0051482 IEA positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0060999 IEA positive regulation of dendritic spine development
GO:0070915 IEA lysophosphatidic acid receptor activity
GO:0071453 IEA cellular response to oxygen levels
GO:0071673 IEA positive regulation of smooth muscle cell chemotaxis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044213 lpar1 lysophosphatidic acid receptor 1 protein_coding Danio_rerio
ENSG00000198121 LPAR1 lysophosphatidic acid receptor 1 protein_coding Homo_sapiens

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