C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Casitas B-lineage lymphoma c
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040525 Cblc 10090 - 7:19778881-19796809 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000043822 Cblc-001 19779718-19796809 protein_coding
  ENSMUST00000108449 Cblc-002 19779718-19796793 protein_coding
  ENSMUST00000125050 Cblc-007 19778881-19789059 processed_transcript
  ENSMUST00000131276 Cblc-004 19790376-19793216 processed_transcript
  ENSMUST00000131602 Cblc-003 19791855-19796805 retained_intron
  ENSMUST00000145755 Cblc-005 19786182-19792245 processed_transcript
  ENSMUST00000148416 Cblc-006 19779625-19785440 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000043822ENSMUST00000108449ENSMUST00000125050ENSMUST00000131276ENSMUST00000131602ENSMUST00000145755ENSMUST00000148416
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000043822 4.767±0.19 0.096±0.00 11.860±1.85 0.062±0.04 4.883±2.06 52.972±4.69 0.207±0.11 9.912±1.78 4.729±3.60 5.012±1.93 N/A 2.428±0.98 1.601±0.61 0.175±0.07
ENSMUST00000108449 0.027±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.312±0.08 N/A
ENSMUST00000125050 N/A 0.234±0.04 N/A 0.072±0.00 1.082±0.00 N/A 0.162±0.07 N/A N/A N/A 0.101±0.00 1.476±0.00 N/A 0.107±0.06
ENSMUST00000131276 0.046±0.00 0.060±0.00 N/A N/A 2.120±0.51 N/A N/A N/A N/A N/A N/A N/A N/A 0.130±0.00
ENSMUST00000131602 N/A N/A N/A 0.034±0.00 N/A N/A N/A N/A N/A N/A N/A 2.401±0.47 N/A N/A
ENSMUST00000145755 0.123±0.00 N/A N/A 0.122±0.00 N/A N/A 0.058±0.00 N/A N/A N/A 0.101±0.03 3.285±2.26 1.106±0.00 N/A
ENSMUST00000148416 N/A 0.061±0.01 N/A 0.076±0.00 N/A N/A N/A N/A N/A N/A 0.108±0.00 0.754±0.32 1.182±0.26 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000151 ISO ubiquitin ligase complex
GO:0001784 IEA phosphotyrosine binding
GO:0004842 ISO ubiquitin-protein transferase activity
GO:0004871 IEA signal transducer activity
GO:0005154 IEA epidermal growth factor receptor binding
GO:0005509 IEA calcium ion binding
GO:0005634 IEA nucleus
GO:0006511 ISO ubiquitin-dependent protein catabolic process
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007175 IEA negative regulation of epidermal growth factor-activated receptor activity
GO:0008270 IEA zinc ion binding
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0017124 IEA SH3 domain binding
GO:0023051 IEA regulation of signaling
GO:0042059 IEA negative regulation of epidermal growth factor receptor signaling pathway
GO:0042787 IEA protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043407 IEA negative regulation of MAP kinase activity
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078217 CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase protein_coding Danio_rerio
ENSG00000142273 CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase protein_coding Homo_sapiens

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