C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: angiomotin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041688 Amot 10090 - X:145446425-145505181 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000112835 Amot-003 145446425-145505144 protein_coding
  ENSMUST00000112836 Amot-201 145446425-145487639 protein_coding
  ENSMUST00000125271 Amot-001 145446425-145487046 protein_coding
  ENSMUST00000135832 Amot-005 145459748-145461912 retained_intron
  ENSMUST00000138187 Amot-002 145451868-145487094 protein_coding
  ENSMUST00000143610 Amot-004 145475720-145505181 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000112835ENSMUST00000112836ENSMUST00000125271ENSMUST00000143610
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000112835 1.543±1.09 2.403±0.65 0.228±0.06 1.532±0.60 3.397±1.72 3.485±1.14 0.934±0.14 5.462±1.31 1.171±0.51 1.802±0.17 5.654±0.85 5.559±2.91 16.870±16.28 1.606±0.50
ENSMUST00000112836 N/A N/A N/A 1.077±0.00 N/A 0.864±0.22 N/A N/A 0.726±0.17 1.090±0.00 2.524±0.89 1.191±0.66 6.310±4.08 0.499±0.00
ENSMUST00000125271 0.756±0.19 1.246±0.43 0.327±0.00 1.094±0.12 1.763±0.00 3.100±1.83 N/A 1.907±0.30 0.455±0.13 0.979±0.00 2.594±0.78 5.035±3.81 14.608±10.91 0.555±0.01
ENSMUST00000143610 2.182±0.00 N/A N/A N/A 3.530±0.00 1.433±0.00 0.731±0.03 3.160±0.77 0.997±0.56 1.311±0.08 N/A 4.431±0.00 N/A 1.047±0.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000717 CIL_000717_0002 CGP X:145290359-145505181
CIL_000718 CIL_000718_0002 CGP X:145446425-147197277

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001570 IMP vasculogenesis
GO:0001701 IMP in utero embryonic development
GO:0001702 IMP gastrulation with mouth forming second
GO:0001725 IEA stress fiber
GO:0001726 IEA ruffle
GO:0003365 IMP establishment of cell polarity involved in ameboidal cell migration
GO:0004872 IEA receptor activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005884 ISS actin filament
GO:0005923 IDA tight junction
GO:0006935 IMP chemotaxis
GO:0008180 IEA COP9 signalosome
GO:0009897 IEA external side of plasma membrane
GO:0009986 IEA cell surface
GO:0016021 IEA integral component of membrane
GO:0016525 IEA negative regulation of angiogenesis
GO:0030027 IDA:ISS lamellipodium
GO:0030036 IMP actin cytoskeleton organization
GO:0030139 IEA endocytic vesicle
GO:0030334 IEA regulation of cell migration
GO:0031410 IDA cytoplasmic vesicle
GO:0034260 IMP negative regulation of GTPase activity
GO:0034613 IMP cellular protein localization
GO:0035329 IEA hippo signaling
GO:0040019 IMP positive regulation of embryonic development
GO:0042074 IMP cell migration involved in gastrulation
GO:0043116 IEA negative regulation of vascular permeability
GO:0043532 ISS angiostatin binding
GO:0043534 IMP blood vessel endothelial cell migration
GO:0043536 IEA positive regulation of blood vessel endothelial cell migration
GO:0048514 IMP blood vessel morphogenesis
GO:0051056 IMP regulation of small GTPase mediated signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078335 amot angiomotin protein_coding Danio_rerio
ENSG00000126016 AMOT angiomotin protein_coding Homo_sapiens

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