C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phospholipase D family, member 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000043648 Pld6 10090 - 11:59783897-59787645 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000051493 Pld6-002 59783897-59787645 processed_transcript
  ENSMUST00000125307 Pld6-001 59784703-59787642 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000051493ENSMUST00000125307
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000051493 0.487±0.11 2.041±0.30 0.207±0.06 0.496±0.25 0.172±0.05 0.288±0.08 0.299±0.02 0.364±0.15 0.482±0.11 0.243±0.07 0.038±0.01 1.128±0.54 0.189±0.13 20.409±10.61
ENSMUST00000125307 0.652±0.21 3.094±1.93 0.432±0.14 0.810±0.41 0.395±0.15 0.435±0.17 0.347±0.14 0.585±0.20 0.880±0.31 0.538±0.21 N/A 1.631±0.89 0.407±0.13 12.710±3.44

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000NS CIL_0000NS_0002 CGP 11:59661305-59787645
CIL_0009A0 CIL_0009A0_0002 VISTA 11:59693037-60296757
CIL_0000NR CIL_0000NR_0002 CGP 11:59783897-59810016

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004519 IEA endonuclease activity
GO:0005741 IDA mitochondrial outer membrane
GO:0005789 TAS endoplasmic reticulum membrane
GO:0007126 IMP meiotic nuclear division
GO:0007286 IMP spermatid development
GO:0008053 ISS mitochondrial fusion
GO:0016021 IEA integral component of membrane
GO:0016042 IEA lipid catabolic process
GO:0030719 IMP P granule organization
GO:0034587 IMP piRNA metabolic process
GO:0035755 ISS cardiolipin hydrolase activity
GO:0042803 ISS protein homodimerization activity
GO:0043046 IMP DNA methylation involved in gamete generation
GO:0046872 IEA metal ion binding
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059951 pld6 phospholipase D family, member 6 protein_coding Danio_rerio
ENSG00000179598 PLD6 phospholipase D family, member 6 protein_coding Homo_sapiens

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