C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: frizzled homolog 1 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000044674 Fzd1 10090 - 5:4753873-4758035 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000054294 Fzd1-001 4753873-4758035 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000054294
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000054294 19.253±6.97 9.897±0.84 50.226±0.59 13.747±8.79 19.487±5.98 21.116±1.00 3.331±0.38 26.241±3.12 3.372±0.77 29.094±1.93 0.753±0.11 21.108±6.05 3.348±1.22 0.807±0.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008EH CIL_0008EH_0002 VISTA 5:4533235-5135697
CIL_0008EJ CIL_0008EJ_0002 VISTA 5:4556663-5159895
CIL_000866 CIL_000866_0002 VISTA 5:4575240-5179650
CIL_00097Q CIL_00097Q_0002 VISTA 5:4707239-5309906
CIL_0003D6 CIL_0003D6_0002 CGP 5:4753873-5420312

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001934 IMP positive regulation of protein phosphorylation
GO:0001944 IBA vasculature development
GO:0003149 IGI membranous septum morphogenesis
GO:0003150 IGI muscular septum morphogenesis
GO:0003151 IGI outflow tract morphogenesis
GO:0004930 IEA G-protein coupled receptor activity
GO:0005102 IEA receptor binding
GO:0005109 IEA frizzled binding
GO:0005737 IBA cytoplasm
GO:0005925 IEA focal adhesion
GO:0006357 IBA regulation of transcription from RNA polymerase II promoter
GO:0007199 IBA G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger
GO:0007223 IBA Wnt signaling pathway, calcium modulating pathway
GO:0007267 IDA cell-cell signaling
GO:0007409 IBA axonogenesis
GO:0007420 IBA brain development
GO:0008406 IBA gonad development
GO:0009986 IEA cell surface
GO:0016021 IEA integral component of membrane
GO:0016055 IGI Wnt signaling pathway
GO:0017147 IPI Wnt-protein binding
GO:0030165 IBA PDZ domain binding
GO:0030514 IDA negative regulation of BMP signaling pathway
GO:0030855 IDA epithelial cell differentiation
GO:0032589 IBA neuron projection membrane
GO:0035414 IDA negative regulation of catenin import into nucleus
GO:0035425 IEA autocrine signaling
GO:0042493 IEA response to drug
GO:0042813 IBA Wnt-activated receptor activity
GO:0044338 IEA canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation
GO:0044339 IEA canonical Wnt signaling pathway involved in osteoblast differentiation
GO:0045177 IBA apical part of cell
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0048286 IBA lung alveolus development
GO:0051091 IEA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060022 IGI hard palate development
GO:0060070 IMP canonical Wnt signaling pathway
GO:0060412 IGI ventricular septum morphogenesis
GO:0090090 IDA negative regulation of canonical Wnt signaling pathway
GO:0090179 IGI planar cell polarity pathway involved in neural tube closure

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041464 fzd1 frizzled homolog 1 protein_coding Danio_rerio
ENSG00000157240 FZD1 frizzled class receptor 1 protein_coding Homo_sapiens

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