C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tet methylcytosine dioxygenase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000047146 Tet1 10090 - 10:62804570-62899118 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000050826 Tet1-201 62804570-62880014 protein_coding
  ENSMUST00000173081 Tet1-002 62839097-62865304 processed_transcript
  ENSMUST00000173087 Tet1-005 62813348-62814539 protein_coding
  ENSMUST00000173905 Tet1-003 62813126-62814541 nonsense_mediated_decay
  ENSMUST00000174121 Tet1-004 62812622-62814540 protein_coding
  ENSMUST00000174189 Tet1-001 62804577-62899118 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000050826ENSMUST00000173905ENSMUST00000174121ENSMUST00000174189
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000050826 0.241±0.09 0.138±0.06 0.315±0.00 0.101±0.04 0.165±0.03 0.124±0.00 0.247±0.19 0.018±0.02 0.128±0.02 0.653±0.44 0.162±0.07 0.020±0.00
ENSMUST00000173905 N/A N/A N/A N/A 0.700±0.00 N/A N/A 0.132±0.05 N/A N/A N/A N/A
ENSMUST00000174121 1.690±0.00 0.173±0.02 N/A N/A 0.274±0.08 0.642±0.00 N/A 0.028±0.01 0.712±0.02 1.486±0.38 N/A N/A
ENSMUST00000174189 N/A N/A N/A N/A N/A N/A 0.054±0.00 0.031±0.00 N/A 0.217±0.00 0.280±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001826 IMP inner cell mass cell differentiation
GO:0005506 ISS iron ion binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006493 IMP protein O-linked glycosylation
GO:0008270 IEA zinc ion binding
GO:0016568 IEA chromatin modification
GO:0019827 IMP stem cell maintenance
GO:0043566 ISS structure-specific DNA binding
GO:0044030 IMP regulation of DNA methylation
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0055114 IEA oxidation-reduction process
GO:0070579 ISS methylcytosine dioxygenase activity
GO:0080111 IMP DNA demethylation
GO:0090310 IEA negative regulation of methylation-dependent chromatin silencing

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075230 tet1 tet methylcytosine dioxygenase 1 protein_coding Danio_rerio
ENSG00000138336 TET1 tet methylcytosine dioxygenase 1 protein_coding Homo_sapiens

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