C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dual specificity phosphatase 18
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000047205 Dusp18 10090 + 11:3895240-3901296 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000055931 Dusp18-201 3895240-3901296 protein_coding
  ENSMUST00000109996 Dusp18-001 3895240-3899353 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000055931ENSMUST00000109996
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000055931 4.923±1.56 2.225±0.49 1.116±0.04 6.925±2.17 3.908±1.15 4.586±1.05 13.995±0.87 3.301±0.40 0.085±0.05 9.456±0.61 5.366±1.59 5.573±2.66 1.038±0.45 6.198±3.73
ENSMUST00000109996 N/A 0.345±0.00 N/A N/A N/A N/A N/A N/A 0.054±0.01 N/A N/A 1.730±0.34 N/A 6.810±0.56

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000188 IEA inactivation of MAPK activity
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0005739 ISS mitochondrion
GO:0005743 ISS mitochondrial inner membrane
GO:0005758 ISS mitochondrial intermembrane space
GO:0006612 ISS protein targeting to membrane
GO:0006626 ISS protein targeting to mitochondrion
GO:0008138 IBA protein tyrosine/serine/threonine phosphatase activity
GO:0016791 ISS phosphatase activity
GO:0017017 IEA MAP kinase tyrosine/serine/threonine phosphatase activity
GO:0031304 ISS intrinsic component of mitochondrial inner membrane
GO:0031314 ISS extrinsic component of mitochondrial inner membrane
GO:0033365 ISS protein localization to organelle
GO:0035335 IBA peptidyl-tyrosine dephosphorylation
GO:0046677 ISS response to antibiotic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078598 si:ch1073-184j22.2 si:ch1073-184j22.2 protein_coding Danio_rerio
ENSDARG00000088800 CABZ01071036.1 Uncharacterized protein protein_coding Danio_rerio
ENSG00000167065 DUSP18 dual specificity phosphatase 18 protein_coding Homo_sapiens

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