C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear receptor subfamily 1, group H, member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000047638 Nr1h4 10090 - 10:89454234-89533585 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000058126 Nr1h4-001 89454234-89506649 protein_coding
  ENSMUST00000105296 Nr1h4-201 89454234-89506658 protein_coding
  ENSMUST00000105297 Nr1h4-002 89454373-89533585 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000058126ENSMUST00000105296ENSMUST00000105297
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000058126 0.094±0.00 N/A 0.216±0.00 0.023±0.00 0.219±0.00 9.058±2.35 N/A 18.408±4.21 13.563±9.65 N/A 0.023±0.01 0.885±0.44 1.774±1.84 0.078±0.01
ENSMUST00000105296 N/A N/A N/A N/A 0.204±0.08 11.059±4.74 N/A 11.508±0.61 10.356±8.05 0.113±0.00 N/A 0.431±0.00 0.590±0.42 0.029±0.00
ENSMUST00000105297 0.186±0.08 6.857±0.72 0.426±0.13 0.025±0.00 0.339±0.17 4.184±0.35 0.161±0.07 N/A 8.397±7.44 0.187±0.04 0.064±0.03 3.151±1.10 0.464±0.28 0.063±0.05

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 IEA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001080 IC nitrogen catabolite activation of transcription from RNA polymerase II promoter
GO:0001190 IEA RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IEA DNA binding
GO:0003690 IEA double-stranded DNA binding
GO:0003700 IGI sequence-specific DNA binding transcription factor activity
GO:0003705 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004872 IEA receptor activity
GO:0004879 IMP ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0004887 IEA thyroid hormone receptor activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005719 IEA nuclear euchromatin
GO:0006109 IEA regulation of carbohydrate metabolic process
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IGI regulation of transcription from RNA polymerase II promoter
GO:0008206 IMP bile acid metabolic process
GO:0008270 IEA zinc ion binding
GO:0009749 IEA response to glucose
GO:0030522 IMP intracellular receptor signaling pathway
GO:0032052 IMP bile acid binding
GO:0032496 IEA response to lipopolysaccharide
GO:0034255 IMP regulation of urea metabolic process
GO:0038181 IEA bile acid receptor activity
GO:0038185 IEA intracellular bile acid receptor signaling pathway
GO:0042277 IEA peptide binding
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0046965 IDA retinoid X receptor binding
GO:0048565 IEA digestive tract development
GO:0070858 IEA negative regulation of bile acid biosynthetic process
GO:0071417 IMP cellular response to organonitrogen compound
GO:1902122 IEA chenodeoxycholic acid binding
GO:1903413 IMP cellular response to bile acid
GO:2000213 IMP positive regulation of glutamate metabolic process
GO:2001250 IMP positive regulation of ammonia assimilation cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057741 nr1h4 nuclear receptor subfamily 1, group H, member 4 protein_coding Danio_rerio
ENSG00000012504 NR1H4 nuclear receptor subfamily 1, group H, member 4 protein_coding Homo_sapiens

Loading