C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: noggin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000048616 Nog 10090 - 11:89300638-89302332 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000061728 Nog-001 89300638-89302332 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000061728
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000061728 1.651±0.86 0.626±0.21 0.517±0.00 2.986±0.51 0.393±0.07 1.876±0.37 0.119±0.06 0.431±0.16 0.041±0.03 0.270±0.08 1.672±0.23 1.532±0.80 0.934±0.73 0.034±0.02

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001501 IMP skeletal system development
GO:0001649 IMP osteoblast differentiation
GO:0001655 IMP urogenital system development
GO:0001657 IDA ureteric bud development
GO:0001701 IMP in utero embryonic development
GO:0001706 IDA endoderm formation
GO:0001707 IDA mesoderm formation
GO:0001837 IMP epithelial to mesenchymal transition
GO:0001839 IMP neural plate morphogenesis
GO:0001843 IMP neural tube closure
GO:0005515 IEA protein binding
GO:0005615 IDA extracellular space
GO:0007389 IMP pattern specification process
GO:0007411 IMP axon guidance
GO:0007417 IMP central nervous system development
GO:0007420 IMP brain development
GO:0008045 IMP motor neuron axon guidance
GO:0009953 IEA dorsal/ventral pattern formation
GO:0010629 IDA negative regulation of gene expression
GO:0019955 IEA cytokine binding
GO:0021510 IMP spinal cord development
GO:0021533 IEA cell differentiation in hindbrain
GO:0021915 IMP neural tube development
GO:0021983 IMP pituitary gland development
GO:0030336 IEA negative regulation of cell migration
GO:0030509 IDA BMP signaling pathway
GO:0030510 IMP regulation of BMP signaling pathway
GO:0030514 IDA negative regulation of BMP signaling pathway
GO:0035019 IEA somatic stem cell maintenance
GO:0042060 IMP wound healing
GO:0042474 IEA middle ear morphogenesis
GO:0042733 IEA embryonic digit morphogenesis
GO:0042803 IEA protein homodimerization activity
GO:0045668 IEA negative regulation of osteoblast differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048318 IMP axial mesoderm development
GO:0048570 IMP notochord morphogenesis
GO:0048646 IGI anatomical structure formation involved in morphogenesis
GO:0048706 IEA embryonic skeletal system development
GO:0048712 IMP negative regulation of astrocyte differentiation
GO:0048762 IMP mesenchymal cell differentiation
GO:0050679 IGI positive regulation of epithelial cell proliferation
GO:0051216 IEA cartilage development
GO:0060044 IMP negative regulation of cardiac muscle cell proliferation
GO:0060173 IEA limb development
GO:0060272 IEA embryonic skeletal joint morphogenesis
GO:0060302 IEA negative regulation of cytokine activity
GO:0060325 IMP face morphogenesis
GO:0060394 IEA negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0060425 IMP lung morphogenesis
GO:0060513 IMP prostatic bud formation
GO:0060676 IDA ureteric bud formation
GO:0060825 IEA fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
GO:0061037 IDA negative regulation of cartilage development
GO:0061053 IMP somite development
GO:0071773 IDA cellular response to BMP stimulus
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway
GO:0090190 IDA positive regulation of branching involved in ureteric bud morphogenesis
GO:0090193 IDA positive regulation of glomerulus development
GO:2000313 IEA regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation
GO:2001234 IMP negative regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053528 NOG (1 of 3) noggin protein_coding Danio_rerio
ENSDARG00000058819 nog1 noggin 1 protein_coding Danio_rerio
ENSDARG00000079003 nog3 noggin 3 protein_coding Danio_rerio
ENSG00000183691 NOG noggin protein_coding Homo_sapiens

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