C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: low density lipoprotein-related protein 1B (deleted in tumors)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000049252 Lrp1b 10090 - 2:40595248-42653598 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000052550 Lrp1b-001 40595248-42653598 protein_coding
  ENSMUST00000129974 Lrp1b-003 40596876-40615251 processed_transcript
  ENSMUST00000133104 Lrp1b-006 42321692-42653256 retained_intron
  ENSMUST00000134032 Lrp1b-004 40677516-40699776 retained_intron
  ENSMUST00000138700 Lrp1b-007 41496148-42653256 retained_intron
  ENSMUST00000142546 Lrp1b-002 40595248-40702800 protein_coding
  ENSMUST00000142688 Lrp1b-005 42649878-42653015 processed_transcript
  ENSMUST00000167270 Lrp1b-201 40801393-41789078 protein_coding
  ENSMUST00000185258 Lrp1b-202 40595534-40627336 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000052550ENSMUST00000129974ENSMUST00000133104ENSMUST00000134032ENSMUST00000138700ENSMUST00000142546ENSMUST00000142688ENSMUST00000167270ENSMUST00000185258
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000052550 N/A 0.008±0.00 N/A 1.592±1.65 N/A N/A N/A N/A 0.002±0.00 N/A N/A 0.005±0.00 0.002±0.00 0.025±0.02
ENSMUST00000129974 0.080±0.01 N/A 0.026±0.00 32.585±0.00 0.174±0.12 0.177±0.00 0.125±0.00 0.108±0.06 0.031±0.01 0.121±0.02 N/A 0.527±0.29 0.487±0.25 0.626±0.00
ENSMUST00000133104 0.022±0.00 0.328±0.20 N/A N/A N/A N/A N/A N/A 0.003±0.00 N/A N/A 0.106±0.00 N/A 0.110±0.00
ENSMUST00000134032 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.036±0.00 0.072±0.00 0.229±0.00
ENSMUST00000138700 0.063±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.008±0.00 N/A 0.006±0.00 0.060±0.00
ENSMUST00000142546 N/A 0.126±0.07 0.008±0.00 0.628±0.15 N/A N/A 0.018±0.01 N/A 0.001±0.00 N/A N/A 0.082±0.02 0.007±0.00 0.065±0.00
ENSMUST00000142688 N/A 0.099±0.00 0.005±0.00 N/A N/A N/A N/A N/A 0.002±0.00 N/A N/A N/A 0.006±0.00 N/A
ENSMUST00000167270 0.017±0.00 0.039±0.02 N/A N/A N/A 0.015±0.00 0.022±0.01 0.004±0.00 0.001±0.00 N/A 0.003±0.00 0.003±0.00 0.003±0.00 N/A
ENSMUST00000185258 N/A N/A N/A N/A N/A N/A N/A N/A 0.005±0.00 N/A N/A 0.086±0.10 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003NW CIL_0003NW_0002 CGP 2:40595248-43682715

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005041 IDA low-density lipoprotein receptor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0006898 IDA receptor-mediated endocytosis
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0043235 ISO receptor complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004789 lrp1ba low density lipoprotein receptor-related protein 1Ba protein_coding Danio_rerio
ENSDARG00000061517 lrp1bb low density lipoprotein receptor-related protein 1Bb protein_coding Danio_rerio
ENSDARG00000094171 lrp1ba low density lipoprotein receptor-related protein 1Ba protein_coding Danio_rerio
ENSG00000168702 LRP1B low density lipoprotein receptor-related protein 1B protein_coding Homo_sapiens

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