C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: matrix metallopeptidase 12
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000049723 Mmp12 10090 + 9:7344381-7369499 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000005950 Mmp12-001 7347374-7360461 protein_coding
  ENSMUST00000065079 Mmp12-004 7347374-7369499 protein_coding
  ENSMUST00000120655 Mmp12-003 7344397-7358464 protein_coding
  ENSMUST00000127722 Mmp12-002 7347406-7358888 nonsense_mediated_decay
  ENSMUST00000138220 Mmp12-007 7347406-7348333 processed_transcript
  ENSMUST00000148005 Mmp12-005 7347406-7357663 retained_intron
  ENSMUST00000150167 Mmp12-006 7344381-7349787 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000005950ENSMUST00000065079ENSMUST00000120655ENSMUST00000127722ENSMUST00000148005ENSMUST00000150167
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000005950 N/A N/A N/A N/A 0.135±0.00 0.083±0.00 N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000065079 N/A N/A 0.499±0.00 N/A N/A 0.215±0.10 N/A N/A N/A N/A 0.047±0.01 1.002±0.75 4.551±0.00
ENSMUST00000120655 1.655±1.36 0.951±0.51 0.654±0.39 N/A 0.498±0.15 0.297±0.14 0.099±0.05 0.424±0.23 0.064±0.02 0.801±0.07 N/A 1.232±1.62 3.740±3.82
ENSMUST00000127722 0.285±0.00 0.453±0.14 0.220±0.15 0.008±0.00 0.274±0.00 N/A N/A 0.152±0.03 0.031±0.01 0.526±0.00 0.015±0.00 2.004±0.95 2.402±0.00
ENSMUST00000148005 0.154±0.08 0.229±0.08 N/A N/A 0.108±0.05 0.141±0.06 N/A 0.105±0.02 0.083±0.04 0.097±0.00 0.010±0.01 0.266±0.18 N/A
ENSMUST00000150167 N/A N/A N/A N/A N/A 0.328±0.05 N/A N/A N/A N/A N/A 1.937±0.15 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004222 IEA metalloendopeptidase activity
GO:0005509 IEA calcium ion binding
GO:0005576 TAS extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0006508 IEA proteolysis
GO:0008270 IEA zinc ion binding
GO:0031012 IEA extracellular matrix
GO:0035313 IEA wound healing, spreading of epidermal cells
GO:0042060 IEA wound healing
GO:0060054 IEA positive regulation of epithelial cell proliferation involved in wound healing

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000262406 MMP12 matrix metallopeptidase 12 (macrophage elastase) protein_coding Homo_sapiens

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