C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: forkhead box C1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000050295 Foxc1 10090 + 13:31806691-31810643 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000062292 Foxc1-001 31806691-31810643 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000062292
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000062292 1.053±0.11 7.400±1.37 3.810±0.02 2.274±0.88 1.407±0.65 0.381±0.04 1.537±0.46 3.913±0.68 0.036±0.03 1.261±0.14 0.321±0.04 1.937±0.78 0.515±0.24 0.039±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00038B CIL_00038B_0002 CGP 13:31625816-31810643
CIL_0005SP CIL_0005SP_0003 CGP 13:31806691-32338712

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000977 IEA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001501 IMP skeletal system development
GO:0001503 IMP ossification
GO:0001541 IMP ovarian follicle development
GO:0001568 IGI blood vessel development
GO:0001654 IMP eye development
GO:0001657 IMP ureteric bud development
GO:0001701 IMP in utero embryonic development
GO:0001756 IGI somitogenesis
GO:0001822 IMP kidney development
GO:0001945 IGI lymph vessel development
GO:0001974 IGI blood vessel remodeling
GO:0003007 IGI heart morphogenesis
GO:0003677 ISS DNA binding
GO:0003700 ISS sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005720 ISS nuclear heterochromatin
GO:0005737 IEA cytoplasm
GO:0006355 ISS regulation of transcription, DNA-templated
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0007219 IGI Notch signaling pathway
GO:0007420 IMP brain development
GO:0007507 ISO heart development
GO:0008134 ISS transcription factor binding
GO:0008301 ISS DNA binding, bending
GO:0008354 IMP germ cell migration
GO:0014032 IGI neural crest cell development
GO:0030199 IMP collagen fibril organization
GO:0030203 IMP glycosaminoglycan metabolic process
GO:0032808 IMP lacrimal gland development
GO:0035050 IGI embryonic heart tube development
GO:0042475 ISS odontogenesis of dentin-containing tooth
GO:0043010 IMP camera-type eye development
GO:0043565 ISS sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045930 ISS negative regulation of mitotic cell cycle
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046620 IGI regulation of organ growth
GO:0048010 IGI vascular endothelial growth factor receptor signaling pathway
GO:0048341 IGI paraxial mesoderm formation
GO:0048762 IMP mesenchymal cell differentiation
GO:0048844 IMP artery morphogenesis
GO:0050880 IGI regulation of blood vessel size
GO:0055010 IGI ventricular cardiac muscle tissue morphogenesis
GO:0060038 IGI cardiac muscle cell proliferation
GO:1902257 IGI negative regulation of apoptotic process involved in outflow tract morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055398 foxc1b forkhead box C1b protein_coding Danio_rerio
ENSDARG00000091481 foxc1a forkhead box C1a protein_coding Danio_rerio
ENSG00000054598 FOXC1 forkhead box C1 protein_coding Homo_sapiens

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