C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: early B cell factor 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000053552 Ebf4 10090 + 2:130295169-130370481 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000110286 Ebf4-001 130295939-130370481 protein_coding
  ENSMUST00000110287 Ebf4-006 130295939-130370481 protein_coding
  ENSMUST00000110288 Ebf4-002 130295169-130370481 protein_coding
  ENSMUST00000126740 Ebf4-004 130295939-130370481 nonsense_mediated_decay
  ENSMUST00000134728 Ebf4-003 130295939-130370481 retained_intron
  ENSMUST00000140169 Ebf4-005 130295939-130370481 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000110286ENSMUST00000110287ENSMUST00000110288ENSMUST00000126740ENSMUST00000134728ENSMUST00000140169
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000110286 1.542±1.91 1.156±0.25 N/A N/A 0.303±0.00 0.415±0.15 N/A 0.350±0.03 0.069±0.03 0.421±0.21 N/A 4.724±2.36 0.350±0.04 0.388±0.09
ENSMUST00000110287 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.117±0.11 3.585±0.47 1.202±0.89 0.108±0.00
ENSMUST00000110288 1.332±1.26 1.159±0.71 1.441±0.23 4.603±0.02 0.234±0.00 0.617±0.00 0.134±0.00 0.222±0.13 0.060±0.04 0.363±0.06 0.383±0.00 4.219±1.17 0.386±0.08 0.261±0.00
ENSMUST00000126740 N/A N/A N/A N/A N/A N/A 0.072±0.00 N/A 0.020±0.00 N/A 0.227±0.10 N/A 0.540±0.00 N/A
ENSMUST00000134728 N/A 1.307±0.06 0.970±0.00 3.147±0.35 N/A 0.320±0.13 N/A N/A 0.072±0.06 0.408±0.08 N/A 3.397±0.79 0.144±0.00 N/A
ENSMUST00000140169 1.148±1.01 0.889±0.22 0.462±0.00 2.012±0.88 0.185±0.00 N/A 0.210±0.05 0.153±0.03 0.075±0.05 0.285±0.01 0.138±0.07 3.134±0.61 N/A 0.358±0.19

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007SG CIL_0007SG_0002 VISTA 2:130051805-130652389
CIL_0000FY CIL_0000FY_0002 CGP 2:130279309-130370481
CIL_0000FX CIL_0000FX_0002 CGP 2:130295169-130397574

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000977 IMP RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228 IDA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IDA DNA binding
GO:0005575 ND cellular_component
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0007275 IEA multicellular organismal development
GO:0008134 IPI transcription factor binding
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0046983 IEA protein dimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000088881 EBF4 early B-cell factor 4 protein_coding Homo_sapiens

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