C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Kruppel-like factor 2 (lung)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000055148 Klf2 10090 + 8:72319033-72321656 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000067912 Klf2-001 72319033-72321656 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000067912
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000067912 19.564±2.68 27.719±6.01 18.988±3.16 2.824±1.03 48.200±31.90 10.615±1.20 14.847±5.62 9.875±1.20 2.988±1.32 78.886±22.95 8.860±2.70 19.358±5.73 7.317±3.39 4.890±1.72

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004DX CIL_0004DX_0003 CGP 8:72319033-72421474

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000902 IMP cell morphogenesis
GO:0001701 IMP in utero embryonic development
GO:0003677 ISS DNA binding
GO:0003700 ISA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0032715 IEA negative regulation of interleukin-6 production
GO:0034101 IMP erythrocyte homeostasis
GO:0034616 IEA response to laminar fluid shear stress
GO:0035264 IMP multicellular organism growth
GO:0036003 IEA positive regulation of transcription from RNA polymerase II promoter in response to stress
GO:0040029 IGI regulation of gene expression, epigenetic
GO:0043249 IMP erythrocyte maturation
GO:0043565 IEA sequence-specific DNA binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0051247 IEA positive regulation of protein metabolic process
GO:0060509 IMP Type I pneumocyte differentiation
GO:0070301 IEA cellular response to hydrogen peroxide
GO:0071347 IEA cellular response to interleukin-1
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0071407 IEA cellular response to organic cyclic compound
GO:0071409 IEA cellular response to cycloheximide
GO:0071499 IEA cellular response to laminar fluid shear stress
GO:1901653 IEA cellular response to peptide

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040432 klf2b Kruppel-like factor 2b protein_coding Danio_rerio
ENSDARG00000042667 klf2a Kruppel-like factor 2a protein_coding Danio_rerio
ENSG00000127528 KLF2 Kruppel-like factor 2 protein_coding Homo_sapiens

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