C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, ionotropic, NMDA2A (epsilon 1)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000059003 Grin2a 10090 - 16:9577710-9994921 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032331 Grin2a-201 9577827-9992533 protein_coding
  ENSMUST00000115835 Grin2a-001 9577710-9994921 protein_coding
  ENSMUST00000156482 Grin2a-002 9991655-9994260 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032331ENSMUST00000115835ENSMUST00000156482
Transcript ID Adipose Adrenal Bladder Brain Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032331 0.008±0.00 0.024±0.01 0.013±0.00 N/A 0.012±0.00 0.014±0.01 0.013±0.00 0.011±0.01 0.019±0.01 0.010±0.00 0.074±0.07 0.007±0.00 0.104±0.03
ENSMUST00000115835 N/A 0.036±0.02 0.020±0.00 0.905±0.80 N/A N/A N/A 0.003±0.00 N/A N/A 0.017±0.00 0.005±0.00 0.031±0.00
ENSMUST00000156482 N/A 0.298±0.16 N/A N/A N/A N/A N/A 0.015±0.00 0.024±0.00 N/A 0.064±0.02 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000EM CIL_0000EM_0002 CGP 16:8830100-9994921

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001964 IMP startle response
GO:0001975 IMP response to amphetamine
GO:0004972 IMP N-methyl-D-aspartate selective glutamate receptor activity
GO:0005234 IBA extracellular-glutamate-gated ion channel activity
GO:0005261 IMP cation channel activity
GO:0005262 IMP calcium channel activity
GO:0005515 IPI protein binding
GO:0005783 IDA endoplasmic reticulum
GO:0006816 IMP calcium ion transport
GO:0007268 IMP synaptic transmission
GO:0007611 IMP learning or memory
GO:0007612 IMP learning
GO:0007613 IMP memory
GO:0007626 TAS locomotory behavior
GO:0008021 IDA synaptic vesicle
GO:0008104 IGI protein localization
GO:0008270 ISS zinc ion binding
GO:0008542 IMP visual learning
GO:0009611 IGI response to wounding
GO:0009986 IDA cell surface
GO:0014069 IDA postsynaptic density
GO:0016020 IDA membrane
GO:0017146 IPI N-methyl-D-aspartate selective glutamate receptor complex
GO:0019233 IMP sensory perception of pain
GO:0022008 IMP neurogenesis
GO:0030054 IEA cell junction
GO:0030431 IMP sleep
GO:0033058 IGI directional locomotion
GO:0034220 IBA ion transmembrane transport
GO:0035235 IEA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0040011 IMP locomotion
GO:0042177 IGI negative regulation of protein catabolic process
GO:0042391 IMP regulation of membrane potential
GO:0042417 IMP dopamine metabolic process
GO:0042428 IMP serotonin metabolic process
GO:0042493 IMP response to drug
GO:0042734 IDA presynaptic membrane
GO:0043005 IDA neuron projection
GO:0043065 IGI positive regulation of apoptotic process
GO:0043197 ISA dendritic spine
GO:0045202 IDA synapse
GO:0045211 IDA postsynaptic membrane
GO:0045471 IMP response to ethanol
GO:0048167 IMP regulation of synaptic plasticity
GO:0050804 IMP regulation of synaptic transmission
GO:0051930 IMP regulation of sensory perception of pain
GO:0060078 IMP regulation of postsynaptic membrane potential
GO:0060079 IMP regulation of excitatory postsynaptic membrane potential
GO:0070588 IMP calcium ion transmembrane transport
GO:0097481 IDA neuronal postsynaptic density
GO:0098655 IMP cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034493 grin2aa glutamate receptor, ionotropic, N-methyl D-aspartate 2A, a protein_coding Danio_rerio
ENSDARG00000070543 grin2ab glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b protein_coding Danio_rerio
ENSG00000183454 GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A protein_coding Homo_sapiens

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