C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SH2 domain containing 3C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000059013 Sh2d3c 10090 + 2:32721055-32755512 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000074248 Sh2d3c-001 32721055-32754994 protein_coding
  ENSMUST00000113242 Sh2d3c-002 32727706-32755512 protein_coding
  ENSMUST00000124133 Sh2d3c-004 32727706-32744844 processed_transcript
  ENSMUST00000131101 Sh2d3c-003 32741490-32747064 protein_coding
  ENSMUST00000139563 Sh2d3c-006 32741492-32743676 processed_transcript
  ENSMUST00000141670 Sh2d3c-005 32735281-32741321 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000074248ENSMUST00000113242ENSMUST00000131101ENSMUST00000139563
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000074248 3.735±0.51 2.903±1.07 1.013±0.12 2.047±0.00 11.442±4.73 1.514±0.48 2.628±0.00 1.202±0.19 1.922±1.37 8.137±2.13 1.487±0.46 2.721±1.31 2.173±1.56 0.208±0.08
ENSMUST00000113242 7.685±4.08 10.204±1.21 1.282±0.28 6.066±6.06 6.593±2.54 3.199±0.49 4.911±0.33 5.437±1.71 1.385±0.56 23.687±9.09 2.628±0.59 5.701±2.33 2.225±0.72 0.465±0.27
ENSMUST00000131101 N/A N/A N/A 7.753±0.35 10.193±0.00 N/A N/A N/A N/A N/A N/A 6.344±2.27 N/A N/A
ENSMUST00000139563 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.349±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008YA CIL_0008YA_0002 VISTA 2:32608279-33209524

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005068 TAS transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0007165 TAS signal transduction
GO:0007169 TAS transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007264 IEA small GTPase mediated signal transduction
GO:0016020 IEA membrane
GO:0043547 IEA positive regulation of GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009081 sh2d3cb SH2 domain containing 3Cb protein_coding Danio_rerio
ENSDARG00000028099 sh2d3ca SH2 domain containing 3Ca protein_coding Danio_rerio
ENSG00000095370 SH2D3C SH2 domain containing 3C protein_coding Homo_sapiens

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