C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine (or cysteine) peptidase inhibitor, clade B, member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000062345 Serpinb2 10090 + 1:107511423-107535478 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000009356 Serpinb2-001 107511423-107525598 protein_coding
  ENSMUST00000064916 Serpinb2-002 107511497-107525592 protein_coding
  ENSMUST00000143832 Serpinb2-004 107522230-107535478 nonsense_mediated_decay
  ENSMUST00000146597 Serpinb2-003 107523944-107532535 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000009356ENSMUST00000064916ENSMUST00000143832ENSMUST00000146597
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000009356 0.109±0.03 0.052±0.00 0.034±0.00 N/A 0.224±0.20 0.063±0.00 0.051±0.03 0.040±0.01 0.080±0.00 2.004±1.18 0.093±0.08 0.203±0.10 0.071±0.03 0.121±0.07
ENSMUST00000064916 N/A 0.050±0.00 0.076±0.00 0.078±0.04 0.454±0.13 0.128±0.00 0.066±0.00 N/A 1.565±0.29 0.603±0.34 0.126±0.12 N/A 0.114±0.04 0.072±0.06
ENSMUST00000143832 N/A N/A N/A N/A N/A N/A 0.069±0.03 0.104±0.03 N/A N/A 0.068±0.00 N/A 0.104±0.00 N/A
ENSMUST00000146597 0.857±0.20 N/A N/A N/A N/A N/A 0.405±0.01 0.193±0.01 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000160 CIL_000160_000S CGP 1:107399655-107535478
CIL_000160 CIL_000160_000R CGP 1:107511423-107549271

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005615 IEA extracellular space
GO:0005737 IBA cytoplasm
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0030162 IBA regulation of proteolysis
GO:0042060 IEA wound healing
GO:0043066 IEA negative regulation of apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014556 serpinb1l3 serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3 protein_coding Danio_rerio
ENSDARG00000057263 zgc:173729 zgc:173729 protein_coding Danio_rerio
ENSDARG00000091801 si:ch73-303g23.4 si:ch73-303g23.4 protein_coding Danio_rerio
ENSDARG00000095830 serpinb1l1 serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1 protein_coding Danio_rerio
ENSDARG00000096888 serpinb1l4 serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 4 protein_coding Danio_rerio
ENSG00000197632 SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 protein_coding Homo_sapiens

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