C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: potassium large conductance calcium-activated channel, subfamily M, alpha member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000063142 Kcnma1 10090 - 14:23289431-24004859 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000065788 Kcnma1-201 23298694-23803304 protein_coding
  ENSMUST00000074983 Kcnma1-202 23299395-23803304 protein_coding
  ENSMUST00000100831 Kcnma1-203 23309015-23803304 protein_coding
  ENSMUST00000112423 Kcnma1-204 23299395-23650189 protein_coding
  ENSMUST00000163322 Kcnma1-205 23309015-23803304 protein_coding
  ENSMUST00000172099 Kcnma1-206 23289431-23803304 protein_coding
  ENSMUST00000177634 Kcnma1-207 23298694-23803304 protein_coding
  ENSMUST00000179097 Kcnma1-208 23298694-23803304 protein_coding
  ENSMUST00000179836 Kcnma1-209 23289431-23803304 protein_coding
  ENSMUST00000188210 Kcnma1-001 23299395-24004859 protein_coding
  ENSMUST00000188285 Kcnma1-003 23299381-24004205 protein_coding
  ENSMUST00000188991 Kcnma1-006 23300021-24004125 protein_coding
  ENSMUST00000190044 Kcnma1-005 23299891-24004205 protein_coding
  ENSMUST00000190339 Kcnma1-002 24002656-24004298 protein_coding
  ENSMUST00000190985 Kcnma1-004 23299891-24003977 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000065788ENSMUST00000074983ENSMUST00000100831ENSMUST00000112423ENSMUST00000163322ENSMUST00000172099ENSMUST00000179097ENSMUST00000179836ENSMUST00000188210ENSMUST00000188991ENSMUST00000190044ENSMUST00000190339ENSMUST00000190985
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000065788 N/A N/A N/A N/A 0.350±0.00 N/A 0.022±0.00 N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000074983 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.290±0.00
ENSMUST00000100831 N/A N/A N/A N/A 0.731±0.00 N/A N/A N/A 0.013±0.00 N/A 1.740±0.18 N/A N/A 0.349±0.00
ENSMUST00000112423 N/A N/A N/A N/A N/A N/A N/A 0.391±0.00 N/A N/A N/A 6.008±0.00 N/A N/A
ENSMUST00000163322 0.700±0.49 N/A 3.831±0.00 N/A 1.189±0.60 3.855±1.44 N/A 0.333±0.17 0.031±0.03 0.288±0.00 N/A 8.409±2.07 0.018±0.01 0.512±0.28
ENSMUST00000172099 N/A N/A N/A N/A N/A N/A N/A 0.363±0.12 N/A N/A N/A N/A N/A N/A
ENSMUST00000179097 N/A N/A N/A 5.133±0.00 0.897±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000179836 0.169±0.00 N/A N/A N/A N/A N/A N/A 0.137±0.00 0.011±0.01 N/A N/A N/A 0.005±0.00 N/A
ENSMUST00000188210 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.992±0.00 N/A N/A N/A
ENSMUST00000188991 1.117±0.00 N/A N/A 1.476±0.00 N/A 4.045±1.37 0.107±0.00 0.241±0.00 0.003±0.00 0.330±0.00 N/A 4.761±0.91 N/A 0.412±0.00
ENSMUST00000190044 0.512±0.00 N/A 6.810±0.77 4.456±0.00 N/A 3.107±1.29 0.096±0.00 0.224±0.00 N/A 0.228±0.00 1.565±0.33 4.337±1.70 N/A 0.188±0.13
ENSMUST00000190339 N/A 8.693±1.69 N/A N/A 0.695±0.00 N/A N/A N/A 0.011±0.01 N/A N/A 8.482±1.52 N/A N/A
ENSMUST00000190985 N/A 11.091±2.68 N/A N/A 0.644±0.16 4.441±2.00 0.154±0.01 0.257±0.00 N/A 0.466±0.17 N/A N/A 0.012±0.00 0.414±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007JX CIL_0007JX_0002 UCNEbase 14:21252402-23394598
CIL_0005E6 CIL_0005E6_0002 CGP 14:22019712-24004859
CIL_000928 CIL_000928_0002 VISTA 14:22714212-23323263
CIL_0008H2 CIL_0008H2_0002 VISTA 14:22740563-23341478
CIL_0008QZ CIL_0008QZ_0002 VISTA 14:22794627-23395917
CIL_0008KV CIL_0008KV_0002 VISTA 14:23186013-23786602
CIL_0008L3 CIL_0008L3_0002 VISTA 14:23193824-23794811
CIL_00087A CIL_00087A_0002 VISTA 14:23220146-23821598
CIL_0004CA CIL_0004CA_0002 CGP 14:23289431-24245920

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IDA response to hypoxia
GO:0003779 IEA actin binding
GO:0005249 IMP voltage-gated potassium channel activity
GO:0005267 IGI potassium channel activity
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005886 IDA plasma membrane
GO:0005901 IEA caveola
GO:0006813 IDA potassium ion transport
GO:0006970 IEA response to osmotic stress
GO:0007268 IMP synaptic transmission
GO:0007605 IMP sensory perception of sound
GO:0007623 IMP circadian rhythm
GO:0007628 IMP adult walking behavior
GO:0008076 IGI voltage-gated potassium channel complex
GO:0009897 IDA external side of plasma membrane
GO:0015269 IDA calcium-activated potassium channel activity
GO:0016021 IDA integral component of membrane
GO:0016324 IDA apical plasma membrane
GO:0019228 IMP neuronal action potential
GO:0030007 IEA cellular potassium ion homeostasis
GO:0032344 IMP regulation of aldosterone metabolic process
GO:0034465 IEA response to carbon monoxide
GO:0042311 IMP vasodilation
GO:0042391 IMP regulation of membrane potential
GO:0042491 IMP auditory receptor cell differentiation
GO:0043065 IEA positive regulation of apoptotic process
GO:0043195 IDA terminal bouton
GO:0045211 IDA postsynaptic membrane
GO:0045475 IMP locomotor rhythm
GO:0045794 IMP negative regulation of cell volume
GO:0046541 IGI saliva secretion
GO:0048469 IMP cell maturation
GO:0050885 IMP neuromuscular process controlling balance
GO:0051260 IDA protein homooligomerization
GO:0051592 IEA response to calcium ion
GO:0060072 IDA large conductance calcium-activated potassium channel activity
GO:0060073 IMP micturition
GO:0060082 IMP eye blink reflex
GO:0060083 IMP smooth muscle contraction involved in micturition
GO:0060087 IMP relaxation of vascular smooth muscle
GO:0070062 IEA extracellular vesicular exosome
GO:0071805 IBA potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060237 kcnma1b potassium large conductance calcium-activated channel, subfamily M, alpha member 1b protein_coding Danio_rerio
ENSDARG00000079840 kcnma1a potassium large conductance calcium-activated channel, subfamily M, alpha member 1a protein_coding Danio_rerio
ENSG00000156113 KCNMA1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 protein_coding Homo_sapiens

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