C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SRY (sex determining region Y)-box 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000063632 Sox11 10090 - 12:27334264-27342574 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000079063 Sox11-001 27334264-27342574 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000079063
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000079063 0.055±0.02 0.110±0.05 0.176±0.03 71.149±50.58 0.100±0.04 0.040±0.03 0.011±0.00 0.049±0.02 0.258±0.28 4.662±0.47 0.011±0.00 0.816±0.39 0.584±0.56 0.145±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001EF CIL_0001EF_0002 CGP 12:26469204-27342574
CIL_0008DV CIL_0008DV_0002 VISTA 12:27263452-27866844

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000976 IDA transcription regulatory region sequence-specific DNA binding
GO:0000979 IEA RNA polymerase II core promoter sequence-specific DNA binding
GO:0001071 IDA nucleic acid binding transcription factor activity
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001105 IDA RNA polymerase II transcription coactivator activity
GO:0001158 IDA enhancer sequence-specific DNA binding
GO:0001501 IMP skeletal system development
GO:0001822 IEA kidney development
GO:0001841 IMP neural tube formation
GO:0002089 IMP lens morphogenesis in camera-type eye
GO:0003151 IMP outflow tract morphogenesis
GO:0003211 IMP cardiac ventricle formation
GO:0003357 IMP noradrenergic neuron differentiation
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003705 ISO RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 ISS cytoplasm
GO:0006366 ISO transcription from RNA polymerase II promoter
GO:0006412 IEA translation
GO:0008135 ISS translation factor activity, nucleic acid binding
GO:0008283 IEA cell proliferation
GO:0008284 IMP positive regulation of cell proliferation
GO:0010628 IMP positive regulation of gene expression
GO:0010629 IMP negative regulation of gene expression
GO:0014003 IEA oligodendrocyte development
GO:0014009 IMP glial cell proliferation
GO:0014032 IMP neural crest cell development
GO:0017015 IEA regulation of transforming growth factor beta receptor signaling pathway
GO:0021510 IMP spinal cord development
GO:0021782 IMP glial cell development
GO:0030182 IEA neuron differentiation
GO:0030513 IMP positive regulation of BMP signaling pathway
GO:0035332 IMP positive regulation of hippo signaling
GO:0035914 IMP skeletal muscle cell differentiation
GO:0045666 IDA positive regulation of neuron differentiation
GO:0045669 ISS positive regulation of osteoblast differentiation
GO:0045778 IMP positive regulation of ossification
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046887 IMP positive regulation of hormone secretion
GO:0048485 IMP sympathetic nervous system development
GO:0048557 IMP embryonic digestive tract morphogenesis
GO:0048704 IMP embryonic skeletal system morphogenesis
GO:0050672 IEA negative regulation of lymphocyte proliferation
GO:0050769 IDA positive regulation of neurogenesis
GO:0060022 IMP hard palate development
GO:0060023 IMP soft palate development
GO:0060174 IMP limb bud formation
GO:0060253 IMP negative regulation of glial cell proliferation
GO:0060412 IMP ventricular septum morphogenesis
GO:0060425 IMP lung morphogenesis
GO:0060548 IMP negative regulation of cell death
GO:0060563 IMP neuroepithelial cell differentiation
GO:0061029 IMP eyelid development in camera-type eye
GO:0061053 IMP somite development
GO:0061303 IMP cornea development in camera-type eye
GO:0061386 IMP closure of optic fissure
GO:0072395 IEA signal transduction involved in cell cycle checkpoint
GO:2000648 ISS positive regulation of stem cell proliferation
GO:2000678 ISS negative regulation of transcription regulatory region DNA binding
GO:2001111 IMP positive regulation of lens epithelial cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077811 sox11a SRY-box containing gene 11a protein_coding Danio_rerio
ENSDARG00000095743 sox11b SRY-box containing gene 11b protein_coding Danio_rerio
ENSG00000176887 SOX11 SRY (sex determining region Y)-box 11 protein_coding Homo_sapiens

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