C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: non-catalytic region of tyrosine kinase adaptor protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000066877 Nck2 10090 + 1:43444579-43570515 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000086421 Nck2-001 43445751-43570515 protein_coding
  ENSMUST00000114744 Nck2-005 43533569-43569342 protein_coding
  ENSMUST00000124817 Nck2-004 43457273-43462222 processed_transcript
  ENSMUST00000136648 Nck2-003 43445751-43462194 processed_transcript
  ENSMUST00000187435 Nck2-007 43444579-43533632 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000086421ENSMUST00000187435
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000086421 17.696±4.42 17.326±3.26 14.681±0.86 14.955±9.95 19.884±11.18 32.050±2.94 5.390±0.93 10.506±1.09 4.737±3.44 22.870±2.37 6.455±0.86 22.799±7.53 10.159±3.71 8.392±5.12
ENSMUST00000187435 N/A N/A N/A N/A 12.215±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00010G CIL_00010G_0002 CGP 1:43123074-43570515
CIL_0003Y7 CIL_0003Y7_0002 CGP 1:43444579-43742578

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005783 IEA endoplasmic reticulum
GO:0006417 IEA regulation of translation
GO:0007015 IMP actin filament organization
GO:0012506 IDA vesicle membrane
GO:0016477 IMP cell migration
GO:0030032 IMP lamellipodium assembly
GO:0030838 IEA positive regulation of actin filament polymerization
GO:0042102 IEA positive regulation of T cell proliferation
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018206 nck2a NCK adaptor protein 2a protein_coding Danio_rerio
ENSDARG00000043361 nck2b NCK adaptor protein 2b protein_coding Danio_rerio
ENSG00000071051 NCK2 NCK adaptor protein 2 protein_coding Homo_sapiens

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