C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: melanocortin 1 receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000074037 Mc1r 10090 + 8:123407082-123410742 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000098324 Mc1r-201 123407082-123410742 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006AO CIL_0006AO_0003 CGP 8:123373824-123410742

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004977 IDA melanocortin receptor activity
GO:0004980 IDA melanocyte-stimulating hormone receptor activity
GO:0005515 IPI protein binding
GO:0005886 IEA plasma membrane
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0010739 IDA positive regulation of protein kinase A signaling
GO:0016021 IEA integral component of membrane
GO:0019233 IMP sensory perception of pain
GO:0030819 IEA positive regulation of cAMP biosynthetic process
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032720 IEA negative regulation of tumor necrosis factor production
GO:0035556 IDA intracellular signal transduction
GO:0042438 IMP melanin biosynthetic process
GO:0042562 IEA hormone binding
GO:0043473 IMP pigmentation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0051897 IDA positive regulation of protein kinase B signaling
GO:0060259 IEA regulation of feeding behavior
GO:0070914 IEA UV-damage excision repair
GO:0090037 IDA positive regulation of protein kinase C signaling
GO:2000253 IEA positive regulation of feeding behavior

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020237 mc1r melanocortin 1 receptor protein_coding Danio_rerio
ENSG00000258839 MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) protein_coding Homo_sapiens

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