C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000087260 Lamtor5 10090 + 3:107278858-107284079 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000145735 Lamtor5-201 107278858-107284079 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000145735
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000145735 51.435±1.32 27.469±3.81 48.250±5.86 20.436±11.53 38.983±8.61 40.701±4.26 33.810±2.93 109.563±8.73 29.384±5.64 49.490±2.08 33.153±1.00 42.170±7.57 33.762±12.93 28.102±11.12

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00075T CIL_00075T_0002 CGP 3:107235531-107284079
CIL_00075S CIL_00075S_0002 CGP 3:107278858-107312115

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 ISS guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005764 ISS lysosome
GO:0005829 IEA cytosol
GO:0008361 ISS regulation of cell size
GO:0019079 IEA viral genome replication
GO:0032008 ISS positive regulation of TOR signaling
GO:0032947 ISS protein complex scaffold
GO:0043066 IEA negative regulation of apoptotic process
GO:0043154 IEA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043547 ISS positive regulation of GTPase activity
GO:0061462 ISS protein localization to lysosome
GO:0071230 ISS cellular response to amino acid stimulus
GO:0071986 ISS Ragulator complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090194 lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 protein_coding Danio_rerio
ENSG00000134248 LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 protein_coding Homo_sapiens

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