C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: FMS-like tyrosine kinase 3 ligand
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000089989 Flt3l 10090 - 7:45131188-45136432 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000085377 Flt3l-003 45131188-45136285 protein_coding
  ENSMUST00000123381 Flt3l-004 45131375-45136081 nonsense_mediated_decay
  ENSMUST00000125500 Flt3l-009 45132114-45136122 protein_coding
  ENSMUST00000126371 Flt3l-008 45131708-45132607 retained_intron
  ENSMUST00000128778 Flt3l-002 45131188-45136417 nonsense_mediated_decay
  ENSMUST00000130628 Flt3l-006 45133526-45136056 protein_coding
  ENSMUST00000134065 Flt3l-005 45131189-45136076 retained_intron
  ENSMUST00000146760 Flt3l-001 45131189-45136432 protein_coding
  ENSMUST00000150673 Flt3l-007 45133882-45134945 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBreastHeartLungENSMUST00000134065
Transcript ID Adrenal Breast Heart Lung
ENSMUST00000134065 19.875±1.12 32.307±10.33 8.378±1.22 35.591±5.59

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001934 IGI positive regulation of protein phosphorylation
GO:0005125 IEA cytokine activity
GO:0005615 IDA extracellular space
GO:0008284 IDA positive regulation of cell proliferation
GO:0009986 IDA cell surface
GO:0016021 IEA integral component of membrane
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0030098 IMP lymphocyte differentiation
GO:0030885 IMP regulation of myeloid dendritic cell activation
GO:0030971 IPI receptor tyrosine kinase binding
GO:0031233 IDA intrinsic component of external side of plasma membrane
GO:0032825 IMP positive regulation of natural killer cell differentiation
GO:0035162 IEA embryonic hemopoiesis
GO:0042803 IPI protein homodimerization activity
GO:0045663 IMP positive regulation of myoblast differentiation
GO:1901741 IMP positive regulation of myoblast fusion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000090554 FLT3LG fms-related tyrosine kinase 3 ligand protein_coding Homo_sapiens

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