C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: hyaluronoglucosaminidase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000010191 Hyal2-201 ENSMUSG00000010047 10090 + 9:107569117-107572776 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000010191
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000010191 17.458±1.74 16.251±4.73 10.752±0.53 10.763±6.36 16.007±7.75 27.264±5.06 5.797±1.37 17.553±3.99 16.795±3.41 30.644±4.56 4.586±1.65 28.120±9.43 17.773±9.44 1.923±0.90

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008D8 CIL_0008D8_0002 VISTA 9:107005935-107609958
CIL_000110 CIL_000110_0002 CGP 9:107563255-107572776

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 ISS Golgi membrane
GO:0000302 ISS response to reactive oxygen species
GO:0001105 NAS RNA polymerase II transcription coactivator activity
GO:0001618 IDA virus receptor activity
GO:0002244 IMP hematopoietic progenitor cell differentiation
GO:0004415 ISS hyalurononglucosaminidase activity
GO:0005540 ISS hyaluronic acid binding
GO:0005764 ISS lysosome
GO:0005829 ISS cytosol
GO:0005902 ISS microvillus
GO:0005975 IEA carbohydrate metabolic process
GO:0006027 ISS glycosaminoglycan catabolic process
GO:0009615 IDA response to virus
GO:0009986 IDA cell surface
GO:0010259 IMP multicellular organismal aging
GO:0010764 ISS negative regulation of fibroblast migration
GO:0016023 ISS cytoplasmic membrane-bounded vesicle
GO:0016324 ISS apical plasma membrane
GO:0019064 ISS fusion of virus membrane with host plasma membrane
GO:0019087 ISS transformation of host cell by virus
GO:0019899 IPI enzyme binding
GO:0030139 ISS endocytic vesicle
GO:0030214 ISS hyaluronan catabolic process
GO:0030294 ISS receptor signaling protein tyrosine kinase inhibitor activity
GO:0030308 ISS negative regulation of cell growth
GO:0031362 IDA anchored component of external side of plasma membrane
GO:0031410 ISS cytoplasmic vesicle
GO:0033906 ISS hyaluronoglucuronidase activity
GO:0035810 ISS positive regulation of urine volume
GO:0042117 ISS monocyte activation
GO:0042307 IDA positive regulation of protein import into nucleus
GO:0043407 ISS negative regulation of MAP kinase activity
GO:0044344 ISS cellular response to fibroblast growth factor stimulus
GO:0045121 IDA membrane raft
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046658 ISS anchored component of plasma membrane
GO:0046718 ISS viral entry into host cell
GO:0048471 ISS perinuclear region of cytoplasm
GO:0048705 IMP skeletal system morphogenesis
GO:0050431 IPI transforming growth factor beta binding
GO:0050729 ISS positive regulation of inflammatory response
GO:0051216 ISS cartilage development
GO:0051607 IDA defense response to virus
GO:0051898 ISS negative regulation of protein kinase B signaling
GO:0060586 IMP multicellular organismal iron ion homeostasis
GO:0061099 ISS negative regulation of protein tyrosine kinase activity
GO:0070295 ISS renal water absorption
GO:0071347 ISS cellular response to interleukin-1
GO:0071493 ISS cellular response to UV-B
GO:0071560 IDA cellular response to transforming growth factor beta stimulus
GO:2000484 ISS positive regulation of interleukin-8 secretion
GO:2000778 ISS positive regulation of interleukin-6 secretion
GO:2001238 IDA positive regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000357750 HYAL2-001 protein_coding Homo_sapiens 0 1502
ENST00000395139 HYAL2-002 protein_coding Homo_sapiens 0 1587
ENST00000442581 HYAL2-004 protein_coding Homo_sapiens 0 1587
ENST00000447092 HYAL2-003 protein_coding Homo_sapiens 0 1504
ENST00000481597 HYAL2-005 retained_intron Homo_sapiens 0 1027

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