C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: c-mer proto-oncogene tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000014505 Mertk-001 ENSMUSG00000014361 10090 + 2:128698956-128802894 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000014505
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000014505 2.843±0.84 2.831±0.34 1.441±0.16 1.049±1.00 1.721±0.46 1.061±0.00 0.725±0.40 5.064±1.86 1.658±0.65 5.457±2.31 0.215±0.05 4.443±1.65 5.476±3.24 0.236±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00047R CIL_00047R_0002 CGP 2:128610104-128802894
CIL_00038G CIL_00038G_0003 CGP 2:128698956-128854261

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001750 IEA photoreceptor outer segment
GO:0001779 IGI natural killer cell differentiation
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005615 IEA extracellular space
GO:0005737 IEA cytoplasm
GO:0006909 IEA phagocytosis
GO:0007283 IGI spermatogenesis
GO:0016021 IEA integral component of membrane
GO:0016028 IEA rhabdomere
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030168 IMP platelet activation
GO:0032940 IMP secretion by cell
GO:0034446 IMP substrate adhesion-dependent cell spreading
GO:0043277 IMP apoptotic cell clearance
GO:0043491 IGI protein kinase B signaling
GO:0050766 IEA positive regulation of phagocytosis
GO:0051250 IGI negative regulation of lymphocyte activation
GO:0060041 IMP retina development in camera-type eye
GO:0060068 IGI vagina development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000295408 MERTK-001 protein_coding Homo_sapiens 0 2621
ENST00000409780 MERTK-002 protein_coding Homo_sapiens 0 2416
ENST00000421804 MERTK-201 protein_coding Homo_sapiens 0 2621
ENST00000439966 MERTK-003 nonsense_mediated_decay Homo_sapiens 0 2418
ENST00000449344 MERTK-005 protein_coding Homo_sapiens 3e-32 143
ENST00000616902 MERTK-202 protein_coding Homo_sapiens 0 492

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