C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: TNF receptor-associated factor 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000021706 Traf3-001 ENSMUSG00000021277 10090 + 12:111166463-111267148 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000021706
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000021706 3.858±2.12 4.424±2.88 6.707±1.67 5.639±3.44 3.190±0.95 2.403±0.66 2.184±0.38 1.862±0.43 1.155±0.45 2.077±0.39 2.518±0.54 2.322±0.82 3.281±1.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009AG CIL_0009AG_0002 VISTA 12:110842738-111443613
CIL_00040T CIL_00040T_0002 CGP 12:111166370-111276426

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001817 IEA:IMP regulation of cytokine production
GO:0002224 IMP toll-like receptor signaling pathway
GO:0004842 IEA ubiquitin-protein transferase activity
GO:0005164 IEA tumor necrosis factor receptor binding
GO:0005515 IPI protein binding
GO:0005768 IEA endosome
GO:0006915 IEA apoptotic process
GO:0008063 IEA Toll signaling pathway
GO:0008270 IEA zinc ion binding
GO:0009898 IDA cytoplasmic side of plasma membrane
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0019901 IPI protein kinase binding
GO:0030162 IMP regulation of proteolysis
GO:0031625 IEA ubiquitin protein ligase binding
GO:0031996 IEA thioesterase binding
GO:0032088 IEA:IMP negative regulation of NF-kappaB transcription factor activity
GO:0032648 IMP regulation of interferon-beta production
GO:0033209 IEA:ISS tumor necrosis factor-mediated signaling pathway
GO:0035631 IDA CD40 receptor complex
GO:0042981 IEA regulation of apoptotic process
GO:0045087 IEA innate immune response
GO:0050688 IEA:IMP regulation of defense response to virus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000347662 TRAF3-201 protein_coding Homo_sapiens 0 2410
ENST00000351691 TRAF3-004 protein_coding Homo_sapiens 0 1639
ENST00000392745 TRAF3-005 protein_coding Homo_sapiens 0 2468
ENST00000539721 TRAF3-002 protein_coding Homo_sapiens 0 1312
ENST00000558700 TRAF3-007 nonsense_mediated_decay Homo_sapiens 0 689
ENST00000559734 TRAF3-008 protein_coding Homo_sapiens 0 848
ENST00000560371 TRAF3-001 protein_coding Homo_sapiens 0 3229

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