C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: twinfilin, actin-binding protein, homolog 1 (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000023087 Twf1-001 ENSMUSG00000022451 10090 - 15:94577951-94589879 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023087
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023087 29.273±1.24 14.602±1.98 40.975±2.15 15.200±8.40 15.728±5.08 38.545±4.59 3.671±1.35 33.751±2.34 12.607±3.08 20.012±1.22 2.031±0.45 28.336±7.81 22.503±11.68 6.370±2.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006R6 CIL_0006R6_0002 CGP 15:94522688-94581815
CIL_0006R5 CIL_0006R5_0002 CGP 15:94543643-94589889
CIL_0006R8 CIL_0006R8_0002 CGP 15:94577951-95096097

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003785 IDA actin monomer binding
GO:0004713 IDA protein tyrosine kinase activity
GO:0005546 IDA phosphatidylinositol-4,5-bisphosphate binding
GO:0005911 IDA cell-cell junction
GO:0015629 IDA actin cytoskeleton
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0030016 IDA myofibril
GO:0030175 IDA filopodium
GO:0030837 IDA negative regulation of actin filament polymerization
GO:0032587 IDA ruffle membrane
GO:0042989 IDA sequestering of actin monomers
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051016 IDA barbed-end actin filament capping

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000395510 TWF1-001 protein_coding Homo_sapiens 0 1657
ENST00000426370 RP13-228J13.6-001 processed_pseudogene Homo_sapiens 0 959
ENST00000546506 TWF1-006 protein_coding Homo_sapiens 0 396
ENST00000546662 TWF1-007 protein_coding Homo_sapiens 0 929
ENST00000547459 TWF1-004 nonsense_mediated_decay Homo_sapiens 0 1539
ENST00000547564 TWF1-010 processed_transcript Homo_sapiens 0 220
ENST00000548315 TWF1-005 protein_coding Homo_sapiens 0 1297
ENST00000548403 TWF1-012 protein_coding Homo_sapiens 0 409
ENST00000550371 TWF1-008 nonsense_mediated_decay Homo_sapiens 0 459
ENST00000551789 TWF1-009 retained_intron Homo_sapiens 0 678
ENST00000552521 TWF1-003 protein_coding Homo_sapiens 0 1539
ENST00000580812 TWF1P1-001 processed_pseudogene Homo_sapiens 0 1293

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