C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: histone deacetylase 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000033501 Hdac6-201 ENSMUSG00000031161 10090 - X:7930122-7947889 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033501
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033501 2.792±1.44 5.107±2.63 2.427±1.11 8.618±3.77 2.506±0.00 2.398±0.97 1.306±0.26 7.992±2.07 2.353±0.54 1.566±0.60 1.212±0.40 3.923±0.94 9.864±7.04 6.328±1.28

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00029K CIL_00029K_0002 CGP X:7930120-7978071

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000118 IEA histone deacetylase complex
GO:0000209 IDA protein polyubiquitination
GO:0001047 IEA core promoter binding
GO:0003779 IEA actin binding
GO:0004407 IDA histone deacetylase activity
GO:0005515 IPI protein binding
GO:0005634 TAS nucleus
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0005874 IEA microtubule
GO:0005875 IEA microtubule associated complex
GO:0005881 IDA cytoplasmic microtubule
GO:0005901 IEA caveola
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006476 IDA protein deacetylation
GO:0006511 IGI ubiquitin-dependent protein catabolic process
GO:0006515 IEA misfolded or incompletely synthesized protein catabolic process
GO:0006886 IEA intracellular protein transport
GO:0007026 IDA negative regulation of microtubule depolymerization
GO:0008013 IEA beta-catenin binding
GO:0008017 IDA microtubule binding
GO:0008270 IEA zinc ion binding
GO:0009636 IEA response to toxic substance
GO:0009967 IEA positive regulation of signal transduction
GO:0010033 IEA response to organic substance
GO:0010469 IEA regulation of receptor activity
GO:0010634 IEA positive regulation of epithelial cell migration
GO:0010870 IEA positive regulation of receptor biosynthetic process
GO:0016234 IEA inclusion body
GO:0016235 IEA aggresome
GO:0016236 IEA macroautophagy
GO:0016575 IDA histone deacetylation
GO:0030286 IEA dynein complex
GO:0030424 IDA axon
GO:0030425 IDA dendrite
GO:0031252 IEA cell leading edge
GO:0031593 IEA polyubiquitin binding
GO:0032041 IEA NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0032418 IEA lysosome localization
GO:0034983 IEA peptidyl-lysine deacetylation
GO:0035967 IEA cellular response to topologically incorrect protein
GO:0040029 IEA regulation of gene expression, epigenetic
GO:0042826 IEA histone deacetylase binding
GO:0042903 IDA tubulin deacetylase activity
GO:0043014 IEA alpha-tubulin binding
GO:0043130 IDA ubiquitin binding
GO:0043162 IMP ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0043204 IDA perikaryon
GO:0043234 IPI protein complex
GO:0043241 IGI protein complex disassembly
GO:0043242 IEA negative regulation of protein complex disassembly
GO:0045598 IMP regulation of fat cell differentiation
GO:0045861 IEA negative regulation of proteolysis
GO:0046969 IEA NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 IEA NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0048156 IEA tau protein binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048487 IDA beta-tubulin binding
GO:0051788 IEA response to misfolded protein
GO:0051879 IEA Hsp90 protein binding
GO:0070201 IMP regulation of establishment of protein localization
GO:0070301 IEA cellular response to hydrogen peroxide
GO:0070840 IEA dynein complex binding
GO:0070842 IGI aggresome assembly
GO:0070845 IEA polyubiquitinated misfolded protein transport
GO:0070846 IMP Hsp90 deacetylation
GO:0070848 IEA response to growth factor
GO:0070932 IEA histone H3 deacetylation
GO:0070933 IEA histone H4 deacetylation
GO:0071218 IMP cellular response to misfolded protein
GO:0090035 IEA positive regulation of chaperone-mediated protein complex assembly
GO:0090042 IMP tubulin deacetylation
GO:0097372 IEA NAD-dependent histone deacetylase activity (H3-K18 specific)
GO:1901300 IEA positive regulation of hydrogen peroxide-mediated programmed cell death

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000334136 HDAC6-001 protein_coding Homo_sapiens 0 2495
ENST00000376610 HDAC6-023 protein_coding Homo_sapiens 0 601
ENST00000376619 HDAC6-017 protein_coding Homo_sapiens 0 2495
ENST00000376643 HDAC6-007 protein_coding Homo_sapiens 0 601
ENST00000423941 HDAC6-020 protein_coding Homo_sapiens 0 361
ENST00000426196 HDAC6-015 protein_coding Homo_sapiens 0 817
ENST00000440653 HDAC6-031 protein_coding Homo_sapiens 0 457
ENST00000441703 HDAC6-028 protein_coding Homo_sapiens 0 446
ENST00000443563 HDAC6-030 protein_coding Homo_sapiens 0 448
ENST00000462730 HDAC6-003 retained_intron Homo_sapiens 0 379
ENST00000465269 HDAC6-004 retained_intron Homo_sapiens 0 379
ENST00000468949 HDAC6-032 retained_intron Homo_sapiens 0 496
ENST00000469223 HDAC6-022 processed_transcript Homo_sapiens 0 680
ENST00000470942 HDAC6-037 retained_intron Homo_sapiens 0 348
ENST00000476625 HDAC6-005 retained_intron Homo_sapiens 0 337
ENST00000477528 HDAC6-002 retained_intron Homo_sapiens 0 2121
ENST00000477561 HDAC6-025 processed_transcript Homo_sapiens 0 669
ENST00000481929 HDAC6-027 retained_intron Homo_sapiens 0 379
ENST00000483656 HDAC6-024 processed_transcript Homo_sapiens 0 580
ENST00000486227 HDAC6-018 retained_intron Homo_sapiens 0 1277
ENST00000486665 HDAC6-036 processed_transcript Homo_sapiens 0 488
ENST00000489352 HDAC6-029 retained_intron Homo_sapiens 0 337
ENST00000493923 HDAC6-009 retained_intron Homo_sapiens 8.99999e-40 167

Loading