C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: 5-hydroxytryptamine (serotonin) receptor 2C
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000036303 Htr2c-002 ENSMUSG00000041380 10090 + X:146962513-147197274 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainLiverLungENSMUST00000036303
Transcript ID Brain Liver Lung
ENSMUST00000036303 2.095±1.01 0.003±0.00 0.147±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000718 CIL_000718_0002 CGP X:145446425-147197277
CIL_000719 CIL_000719_0002 CGP X:146962513-147429192

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001587 ISS Gq/11-coupled serotonin receptor activity
GO:0001662 IMP behavioral fear response
GO:0004993 IMP serotonin receptor activity
GO:0005887 ISS integral component of plasma membrane
GO:0007208 IMP phospholipase C-activating serotonin receptor signaling pathway
GO:0007626 IEA locomotory behavior
GO:0007631 IMP feeding behavior
GO:0031644 IMP regulation of neurological system process
GO:0032098 IMP regulation of appetite
GO:0043397 IMP regulation of corticotropin-releasing hormone secretion
GO:0045600 IMP positive regulation of fat cell differentiation
GO:0051378 ISO serotonin binding
GO:0051482 IMP positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000276198 HTR2C-002 protein_coding Homo_sapiens 0 2388
ENST00000371950 HTR2C-003 protein_coding Homo_sapiens 0 2388
ENST00000371951 HTR2C-001 protein_coding Homo_sapiens 0 1543

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