C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: elastase, neutrophil expressed
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000046091 Elane-201 ENSMUSG00000020125 10090 + 10:79886312-79888216 protein_coding

Mus musculus EnsemblGRCm38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000046091
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000046091 0.698±0.45 0.406±0.29 0.060±0.04 0.189±0.00 2.116±0.87 0.107±0.05 0.097±0.05 0.067±0.00 35.232±37.66 0.344±0.10 0.111±0.03 0.482±0.36 0.042±0.02 0.089±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XG CIL_0008XG_0002 VISTA 10:79539861-80142369
CIL_0000HZ CIL_0000HZ_0002 CGP 10:79874476-79888216
CIL_000316 CIL_000316_0002 CGP 10:79886312-79892656

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001106 IEA RNA polymerase II transcription corepressor activity
GO:0001878 IMP response to yeast
GO:0002020 IEA protease binding
GO:0002438 IDA acute inflammatory response to antigenic stimulus
GO:0004175 IEA endopeptidase activity
GO:0004252 IDA serine-type endopeptidase activity
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0006909 IMP phagocytosis
GO:0008201 IEA heparin binding
GO:0008233 IEA peptidase activity
GO:0009411 IEA response to UV
GO:0009986 IEA cell surface
GO:0017053 IEA transcriptional repressor complex
GO:0019955 IEA cytokine binding
GO:0030141 IEA secretory granule
GO:0032496 IGI response to lipopolysaccharide
GO:0042742 IEA defense response to bacterium
GO:0044130 IGI negative regulation of growth of symbiont in host
GO:0045079 IEA negative regulation of chemokine biosynthetic process
GO:0045415 IEA negative regulation of interleukin-8 biosynthetic process
GO:0045416 IEA positive regulation of interleukin-8 biosynthetic process
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0050778 IGI positive regulation of immune response
GO:0050832 IGI defense response to fungus
GO:0050900 IMP leukocyte migration
GO:0070062 IEA extracellular vesicular exosome
GO:0070947 IMP neutrophil mediated killing of fungus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000263621 ELANE-201 protein_coding Homo_sapiens 0 344
ENST00000590230 ELANE-001 protein_coding Homo_sapiens 0 344
ENST00000615489 ELANE-202 protein_coding Homo_sapiens 0 344

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