C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: GATA binding protein 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000047762 Gata6-201 ENSMUSG00000005836 10090 + 18:11052510-11085635 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000047762
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000047762 7.051±2.51 24.366±18.38 16.911±1.03 0.100±0.07 4.016±2.59 15.290±7.72 16.424±2.57 0.849±0.35 2.864±0.71 12.490±2.48 0.115±0.04 20.481±13.95 4.195±2.19 1.696±0.83

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005NR CIL_0005NR_0002 CGP 18:10725548-11085635
CIL_0008XC CIL_0008XC_0004 VISTA 18:10777951-11378500

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0000981 IEA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001103 IPI RNA polymerase II repressing transcription factor binding
GO:0001701 IMP in utero embryonic development
GO:0001889 IMP liver development
GO:0003148 IEA outflow tract septum morphogenesis
GO:0003309 IMP type B pancreatic cell differentiation
GO:0003310 IMP pancreatic A cell differentiation
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0006644 IGI phospholipid metabolic process
GO:0007493 IDA endodermal cell fate determination
GO:0008134 IPI transcription factor binding
GO:0008270 IEA zinc ion binding
GO:0008584 IEA male gonad development
GO:0010468 IGI regulation of gene expression
GO:0014898 IMP cardiac muscle hypertrophy in response to stress
GO:0019901 IEA protein kinase binding
GO:0030855 IMP epithelial cell differentiation
GO:0031016 IMP pancreas development
GO:0032911 IEA negative regulation of transforming growth factor beta1 production
GO:0032912 IEA negative regulation of transforming growth factor beta2 production
GO:0035239 IGI tube morphogenesis
GO:0035987 IMP endodermal cell differentiation
GO:0042493 IEA response to drug
GO:0043066 IEA negative regulation of apoptotic process
GO:0043565 IDA sequence-specific DNA binding
GO:0043627 IDA response to estrogen
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045766 IEA positive regulation of angiogenesis
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048645 IMP organ formation
GO:0048738 IGI cardiac muscle tissue development
GO:0051145 IEA smooth muscle cell differentiation
GO:0051891 IEP positive regulation of cardioblast differentiation
GO:0055007 IEP cardiac muscle cell differentiation
GO:0060045 IGI positive regulation of cardiac muscle cell proliferation
GO:0060430 IGI lung saccule development
GO:0060486 IGI Clara cell differentiation
GO:0060510 IGI Type II pneumocyte differentiation
GO:0060575 ISO intestinal epithelial cell differentiation
GO:0060947 IEA cardiac vascular smooth muscle cell differentiation
GO:0070848 IEA response to growth factor
GO:0071158 IEA positive regulation of cell cycle arrest
GO:0071371 IDA cellular response to gonadotropin stimulus
GO:0071456 IEA cellular response to hypoxia
GO:0071773 IDA cellular response to BMP stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000049129 gata4-201 protein_coding Danio_rerio 3e-38 165
ENSDART00000099559 gata4-001 protein_coding Danio_rerio 3e-38 165
ENST00000269216 GATA6-001 protein_coding Homo_sapiens 0 2820
ENST00000581694 GATA6-002 protein_coding Homo_sapiens 0 1869

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