C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: DNA methyltransferase 3B
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000056495 Dnmt3b-201 ENSMUSG00000027478 10090 + 2:153649454-153687726 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; KidneyLiverOvaryPlacentaENSMUST00000056495
Transcript ID Kidney Liver Ovary Placenta
ENSMUST00000056495 0.117±0.03 0.266±0.08 0.446±0.10 0.595±0.16

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008A4 CIL_0008A4_0002 VISTA 2:153181176-153785061
CIL_0008NQ CIL_0008NQ_0002 VISTA 2:153260290-153861940
CIL_0008QN CIL_0008QN_0002 VISTA 2:153551282-154154369
CIL_00036W CIL_00036W_0002 CGP 2:153616933-153687730
CIL_0001KC CIL_0001KC_0002 CGP 2:153649450-153773310

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000792 IDA heterochromatin
GO:0003677 IDA DNA binding
GO:0003714 IEA transcription corepressor activity
GO:0003886 IDA DNA (cytosine-5-)-methyltransferase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005720 IDA nuclear heterochromatin
GO:0005737 IEA cytoplasm
GO:0006306 IGI DNA methylation
GO:0006346 IGI methylation-dependent chromatin silencing
GO:0006349 IMP regulation of gene expression by genetic imprinting
GO:0010212 IEA response to ionizing radiation
GO:0010424 IEA DNA methylation on cytosine within a CG sequence
GO:0010628 IEA positive regulation of gene expression
GO:0031503 IDA protein complex localization
GO:0042493 IEA response to drug
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0045322 IEA unmethylated CpG binding
GO:0045666 IEA positive regulation of neuron differentiation
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0046498 IEA S-adenosylhomocysteine metabolic process
GO:0046499 IEA S-adenosylmethioninamine metabolic process
GO:0051571 IEA positive regulation of histone H3-K4 methylation
GO:0051573 IEA negative regulation of histone H3-K9 methylation
GO:0051718 IEA DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates
GO:0071230 IDA cellular response to amino acid stimulus
GO:0090116 IDA C-5 methylation of cytosine

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000201963 DNMT3B-004 protein_coding Homo_sapiens 0 1504
ENST00000328111 DNMT3B-001 protein_coding Homo_sapiens 0 2163
ENST00000348286 DNMT3B-003 protein_coding Homo_sapiens 0 595
ENST00000353855 DNMT3B-002 protein_coding Homo_sapiens 0 1504
ENST00000443239 DNMT3B-006 protein_coding Homo_sapiens 0 595
ENST00000456297 DNMT3B-005 protein_coding Homo_sapiens 0 595

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