C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: WNK lysine deficient protein kinase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000060043 Wnk1-001 ENSMUSG00000045962 10090 - 6:119923969-120038672 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastHeartLiverMusclePlacentaTestisENSMUST00000060043
Transcript ID Brain Breast Heart Liver Muscle Placenta Testis
ENSMUST00000060043 7.963±1.55 9.405±3.88 17.979±3.69 2.815±1.25 9.211±3.19 7.381±4.86 19.472±7.79

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007TY CIL_0007TY_0002 VISTA 6:119665436-120266145
CIL_0008AW CIL_0008AW_0002 VISTA 6:119874234-120475208
CIL_0006C0 CIL_0006C0_0002 CGP 6:119902698-120038672
CIL_0006BZ CIL_0006BZ_0002 CGP 6:119923969-120200339

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003084 IMP positive regulation of systemic arterial blood pressure
GO:0004672 IDA protein kinase activity
GO:0004860 IEA protein kinase inhibitor activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0006468 IDA protein phosphorylation
GO:0006469 IEA negative regulation of protein kinase activity
GO:0006811 IDA ion transport
GO:0010923 ISS negative regulation of phosphatase activity
GO:0019902 ISS phosphatase binding
GO:0050794 IDA regulation of cellular process
GO:0090188 IMP negative regulation of pancreatic juice secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000315939 WNK1-001 protein_coding Homo_sapiens 0 7978
ENST00000340908 WNK1-201 protein_coding Homo_sapiens 0 4237
ENST00000447667 WNK1-003 protein_coding Homo_sapiens 0 1417
ENST00000530271 WNK1-202 protein_coding Homo_sapiens 0 4377
ENST00000534872 WNK1-008 protein_coding Homo_sapiens 0 520
ENST00000535572 WNK1-002 protein_coding Homo_sapiens 0 4244
ENST00000535698 WNK1-015 protein_coding Homo_sapiens 0 769
ENST00000537603 WNK1-013 retained_intron Homo_sapiens 0 505
ENST00000537687 WNK1-203 protein_coding Homo_sapiens 0 4593
ENST00000538787 WNK1-005 processed_transcript Homo_sapiens 0 340
ENST00000540360 WNK1-004 processed_transcript Homo_sapiens 0 889
ENST00000540885 WNK1-011 retained_intron Homo_sapiens 0 872
ENST00000542424 WNK1-014 retained_intron Homo_sapiens 0 697
ENST00000542543 WNK1-009 retained_intron Homo_sapiens 1e-24 117
ENST00000543065 WNK1-017 protein_coding Homo_sapiens 1e-29 132
ENST00000544559 WNK1-018 protein_coding Homo_sapiens 4e-31 137
ENST00000544965 WNK1-016 protein_coding Homo_sapiens 0 342
ENST00000545055 WNK1-010 retained_intron Homo_sapiens 0 483
ENST00000545285 WNK1-006 protein_coding Homo_sapiens 0 276

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