C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: phosphoinositide-3-kinase, regulatory subunit 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000060441 Pik3r6-201 ENSMUSG00000046207 10090 + 11:68503019-68552698 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000060441
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000060441 2.340±1.66 0.902±0.06 0.580±0.09 0.628±0.01 2.340±0.85 0.378±0.23 2.327±0.43 1.248±0.27 0.608±0.43 3.794±1.08 0.518±0.18 1.322±0.41 0.361±0.02 1.890±0.18

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00088C CIL_00088C_0002 VISTA 11:68323475-68924174
CIL_0009AZ CIL_0009AZ_0002 VISTA 11:68337699-68940744
CIL_00033Z CIL_00033Z_0002 CGP 11:68503019-68558245

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0005515 IEA protein binding
GO:0005944 IDA phosphatidylinositol 3-kinase complex, class IB
GO:0007186 IDA G-protein coupled receptor signaling pathway
GO:0016020 IDA membrane
GO:0043406 IDA positive regulation of MAP kinase activity
GO:0043551 IEA regulation of phosphatidylinositol 3-kinase activity
GO:0045766 ISS positive regulation of angiogenesis
GO:0046854 IDA phosphatidylinositol phosphorylation
GO:0046934 IDA phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0046935 IDA 1-phosphatidylinositol-3-kinase regulator activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000611951 PIK3R6-003 nonsense_mediated_decay Homo_sapiens 0 1520
ENST00000613555 PIK3R6-001 nonsense_mediated_decay Homo_sapiens 0 1079
ENST00000614407 PIK3R6-002 protein_coding Homo_sapiens 0 1910
ENST00000619866 PIK3R6-201 protein_coding Homo_sapiens 0 1934

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