C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein kinase C, beta
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000064989 Prkcb-001 ENSMUSG00000052889 10090 + 7:122289297-122628655 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000064989
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000064989 2.172±0.99 1.205±0.30 70.304±0.00 9.569±3.30 0.860±0.37 0.531±0.17 0.704±0.24 0.322±0.22 2.621±0.39 0.023±0.01 1.425±0.23 0.189±0.25 1.000±0.14

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006CY CIL_0006CY_0002 CGP 7:122219496-122634402
CIL_0003VA CIL_0003VA_0003 CGP 7:122288751-122769393

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003682 ISS chromatin binding
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004697 IDA protein kinase C activity
GO:0005080 IEA protein kinase C binding
GO:0005246 IDA calcium channel regulator activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 ISS nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006357 ISS regulation of transcription from RNA polymerase II promoter
GO:0006468 IDA protein phosphorylation
GO:0006816 IDA calcium ion transport
GO:0006874 IDA cellular calcium ion homeostasis
GO:0006915 IEA apoptotic process
GO:0008270 IEA zinc ion binding
GO:0010829 IMP negative regulation of glucose transport
GO:0030374 ISS ligand-dependent nuclear receptor transcription coactivator activity
GO:0030949 IMP positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0035403 ISS histone kinase activity (H3-T6 specific)
GO:0035408 ISS histone H3-T6 phosphorylation
GO:0035556 IEA intracellular signal transduction
GO:0042113 IMP B cell activation
GO:0042393 ISS histone binding
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045766 IMP positive regulation of angiogenesis
GO:0046627 ISS negative regulation of insulin receptor signaling pathway
GO:0050681 ISS androgen receptor binding
GO:0050853 IMP B cell receptor signaling pathway
GO:0050861 IMP positive regulation of B cell receptor signaling pathway
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0070062 IEA extracellular vesicular exosome
GO:0071322 IDA cellular response to carbohydrate stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000029451 prkcbb-001 protein_coding Danio_rerio 0 1428
ENSDART00000006211 prkcba-001 protein_coding Danio_rerio 0 974
ENSDART00000137211 prkcba-002 protein_coding Danio_rerio 0 315
ENSDART00000142610 prkcg-001 protein_coding Danio_rerio 0 255
ENST00000263431 PRKCG-001 protein_coding Homo_sapiens 0 233
ENST00000284384 PRKCA-003 nonsense_mediated_decay Homo_sapiens 0 255
ENST00000303531 PRKCB-002 protein_coding Homo_sapiens 0 3208
ENST00000321728 PRKCB-001 protein_coding Homo_sapiens 0 2543
ENST00000413366 PRKCA-002 protein_coding Homo_sapiens 0 989
ENST00000419486 PRKCG-006 protein_coding Homo_sapiens 0 233
ENST00000463752 PRKCB-008 retained_intron Homo_sapiens 0 222
ENST00000472066 PRKCB-007 protein_coding Homo_sapiens 0 521
ENST00000474397 PRKCG-005 protein_coding Homo_sapiens 0 233
ENST00000479081 PRKCG-004 protein_coding Homo_sapiens 0 222
ENST00000482000 PRKCB-006 processed_transcript Homo_sapiens 0 399
ENST00000486868 PRKCB-005 retained_intron Homo_sapiens 0 414
ENST00000487674 PRKCB-009 retained_intron Homo_sapiens 0 540
ENST00000498058 PRKCB-003 protein_coding Homo_sapiens 0 337
ENST00000498739 PRKCB-004 protein_coding Homo_sapiens 0 497
ENST00000578063 PRKCA-001 nonsense_mediated_decay Homo_sapiens 0 521
ENST00000583361 PRKCA-005 processed_transcript Homo_sapiens 0 209
ENST00000583775 PRKCA-004 retained_intron Homo_sapiens 1e-31 139

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