C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: WNK lysine deficient protein kinase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000088646 Wnk1-202 ENSMUSG00000045962 10090 - 6:119923971-120038655 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaENSMUST00000088646
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta
ENSMUST00000088646 7.209±0.00 8.491±0.18 4.340±0.00 3.687±0.00 22.932±0.74 6.464±3.25 9.426±1.60 12.105±0.13 3.563±2.17 16.856±3.25 11.749±4.53 13.770±7.62

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007TY CIL_0007TY_0002 VISTA 6:119665436-120266145
CIL_0008AW CIL_0008AW_0002 VISTA 6:119874234-120475208
CIL_0006C0 CIL_0006C0_0002 CGP 6:119902698-120038672
CIL_0006BZ CIL_0006BZ_0002 CGP 6:119923969-120200339

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003084 IMP positive regulation of systemic arterial blood pressure
GO:0004672 IDA protein kinase activity
GO:0004860 IEA protein kinase inhibitor activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0006468 IDA protein phosphorylation
GO:0006469 IEA negative regulation of protein kinase activity
GO:0006811 IDA ion transport
GO:0010923 ISS negative regulation of phosphatase activity
GO:0019902 ISS phosphatase binding
GO:0050794 IDA regulation of cellular process
GO:0090188 IMP negative regulation of pancreatic juice secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000315939 WNK1-001 protein_coding Homo_sapiens 0 2894
ENST00000340908 WNK1-201 protein_coding Homo_sapiens 0 2726
ENST00000447667 WNK1-003 protein_coding Homo_sapiens 0 1417
ENST00000530271 WNK1-202 protein_coding Homo_sapiens 0 2726
ENST00000534872 WNK1-008 protein_coding Homo_sapiens 0 520
ENST00000535572 WNK1-002 protein_coding Homo_sapiens 0 2907
ENST00000535698 WNK1-015 protein_coding Homo_sapiens 4.00001e-40 169
ENST00000537603 WNK1-013 retained_intron Homo_sapiens 0 505
ENST00000537687 WNK1-203 protein_coding Homo_sapiens 0 2726
ENST00000538787 WNK1-005 processed_transcript Homo_sapiens 0 340
ENST00000540360 WNK1-004 processed_transcript Homo_sapiens 0 889
ENST00000540885 WNK1-011 retained_intron Homo_sapiens 0 872
ENST00000542424 WNK1-014 retained_intron Homo_sapiens 0 697
ENST00000542543 WNK1-009 retained_intron Homo_sapiens 1e-24 117
ENST00000543065 WNK1-017 protein_coding Homo_sapiens 1e-29 132
ENST00000544559 WNK1-018 protein_coding Homo_sapiens 4e-31 137
ENST00000544965 WNK1-016 protein_coding Homo_sapiens 0 342
ENST00000545055 WNK1-010 retained_intron Homo_sapiens 0 483
ENST00000545285 WNK1-006 protein_coding Homo_sapiens 0 460

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