C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: 5-hydroxytryptamine (serotonin) receptor 2C
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000096299 Htr2c-001 ENSMUSG00000041380 10090 + X:146962514-147197277 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainENSMUST00000096299
Transcript ID Brain
ENSMUST00000096299 0.272±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000718 CIL_000718_0002 CGP X:145446425-147197277
CIL_000719 CIL_000719_0002 CGP X:146962513-147429192

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001587 ISS Gq/11-coupled serotonin receptor activity
GO:0001662 IMP behavioral fear response
GO:0004993 IMP serotonin receptor activity
GO:0005886 IEA plasma membrane
GO:0005887 ISS integral component of plasma membrane
GO:0006182 IEA cGMP biosynthetic process
GO:0006874 IEA cellular calcium ion homeostasis
GO:0007200 IEA phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007208 IMP phospholipase C-activating serotonin receptor signaling pathway
GO:0007210 IEA serotonin receptor signaling pathway
GO:0007626 IEA locomotory behavior
GO:0007631 IMP feeding behavior
GO:0008144 IEA drug binding
GO:0010513 IEA positive regulation of phosphatidylinositol biosynthetic process
GO:0031644 IMP regulation of neurological system process
GO:0032098 IMP regulation of appetite
GO:0042493 IEA response to drug
GO:0043397 IMP regulation of corticotropin-releasing hormone secretion
GO:0045600 IMP positive regulation of fat cell differentiation
GO:0051209 IEA release of sequestered calcium ion into cytosol
GO:0051378 ISO serotonin binding
GO:0051482 IMP positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0070374 IEA positive regulation of ERK1 and ERK2 cascade
GO:0071886 IEA 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000276198 HTR2C-002 protein_coding Homo_sapiens 0 2388
ENST00000371950 HTR2C-003 protein_coding Homo_sapiens 0 2388
ENST00000371951 HTR2C-001 protein_coding Homo_sapiens 0 1543

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