C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000099080 Prex1-003 ENSMUSG00000039621 10090 - 2:166566960-166638968 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; TestisENSMUST00000099080
Transcript ID Testis
ENSMUST00000099080 0.727±0.34

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008NU CIL_0008NU_0002 VISTA 2:166052865-166654821
CIL_00025A CIL_00025A_0002 CGP 2:166073089-166713832
CIL_0008GE CIL_0008GE_0002 VISTA 2:166140620-166743127

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0007186 IGI G-protein coupled receptor signaling pathway
GO:0030217 IGI T cell differentiation
GO:0030593 IGI neutrophil chemotaxis
GO:0032855 IGI positive regulation of Rac GTPase activity
GO:0035556 IEA intracellular signal transduction
GO:0045785 IGI positive regulation of cell adhesion
GO:0072593 IGI reactive oxygen species metabolic process
GO:1900026 IGI positive regulation of substrate adhesion-dependent cell spreading

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000078022 prex1-201 protein_coding Danio_rerio 8e-26 124
ENSDART00000138289 prex1-001 protein_coding Danio_rerio 8e-26 124
ENST00000371941 PREX1-001 protein_coding Homo_sapiens 0 5114
ENST00000482556 PREX1-002 nonsense_mediated_decay Homo_sapiens 0 2423

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